Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours - Yao, Han; Lan, Jiang; Li, Chushu; Shi, Hubing; Brosseau, Jean-Philippe; Wang, Huanbin; Lu, Haojie; Fang, Caiyun; Zhang, Yao; Liang, Lunxi; Zhou, Xiaolin; Wang, Chaojun; et al. (Nature biomedical engineering, 2019)
Keywords: 45/70; 45/77; 45/91; 631/154/555; 631/250/251/1574; 631/67/580; 64/60; 692/4017; 692/4028/67/1059; 82/1; 82/29; 96/106; 96/31; 96/35; 96/95; Acyltransferase; Acyltransferases - metabolism; Animals; Antibodies; Apoptosis; B7-H1 Antigen - metabolism; Biomedical and Life Sciences; Biomedical Engineering/Biotechnology; Biomedicine; Cancer; Cell death; Cell Line, Tumor; Cell membranes; Cell surface; Degradation; Domains; Humans; Immune checkpoint; Immune response; Immune response (cell-mediated); Immunity; Immunosurveillance; Intracellular; Ligands; Lipids; Lipoylation; Lymphocytes T; Lysosomes; Lysosomes - metabolism; Mice; Neoplasms - immunology; Palmitoylation; Palmitoyltransferase; PD-1 protein; PD-L1 protein; Peptides - metabolism; T-Lymphocytes - immunology; Tumors; Ubiquitination