L-type calcium channels in exocytosis and endocytosis of chromaffin cells

• Published in: Pflügers Archiv Vol. 470; no. 1; pp. 53 - 60
• Main Authors: Nanclares, Carmen, Baraibar, Andrés M., Gandía, Luis
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 2018; Springer Nature B.V
• Subjects: Action Potentials; Animals; Biomedical and Life Sciences; Biomedicine; Calcium Channel Blockers - pharmacology; Calcium channels; Calcium channels (L-type); Calcium channels (voltage-gated); Calcium Channels, L-Type - metabolism; Calcium influx; Catecholamines; Cell Biology; Channel gating; Chromaffin cells; Chromaffin Cells - drug effects; Chromaffin Cells - metabolism; Chromaffin Cells - physiology; Depolarization; Endocytosis; Exocytosis; Human Physiology; Humans; Invited Review; Molecular Medicine; Neurosciences; Neurotransmitter release; Plasma membranes; Receptors; Chromaffin cells; Calcium channels; Endocytosis; Exocytosis

The coexistence of different subtypes of voltage-dependent calcium channels (VDCC) within the same chromaffin cell (CC) and the marked interspecies variability in the proportion of VDCC subtypes that are present in the plasmalemma of the CCs raises the question on their roles in controlling differen...