Molecular Imaging of Myocardial Fibroblast Activation in Patients with Advanced Aortic Stenosis Before Transcatheter Aortic Valve Replacement: A Pilot Study - Diekmann, Johanna; Neuser, Jonas; Röhrich, Manuel; Derlin, Thorsten; Zwadlo, Carolin; Koenig, Tobias; Weiberg, Desiree; Jäckle, Felix; Kempf, Tibor; Ross, Tobias L.; Tillmanns, Jochen; Thackeray, James T.; et al. (Journal of Nuclear Medicine, 2023)
Keywords: Aorta; Aortic stenosis; Aortic valve; Aortic Valve - diagnostic imaging; Aortic Valve - surgery; Aortic Valve Stenosis - diagnostic imaging; Aortic Valve Stenosis - surgery; Biomarkers; Brain; Brain natriuretic peptide; Coronary artery disease; Correlation; Echocardiography; Ejection fraction; Fibroblast activation protein; Fibroblasts; Fibrosis; Gallium Radioisotopes; Heart diseases; Heart valves; Humans; Hypertension; Hypertension - surgery; Magnetic resonance imaging; Medical imaging; Molecular Imaging; Natriuretic Peptide, Brain; Neuroimaging; Parameter identification; Patients; Peptides; Pilot Projects; Positron emission; Positron emission tomography; Relaxation time; Spin-lattice relaxation; Statistical analysis; Stroke Volume - physiology; Subgroups; Substrates; Transcatheter Aortic Valve Replacement - methods; Treatment Outcome; Ventricle; Ventricular Function, Left - physiology; aortic stenosis; molecular imaging; fibroblast activation protein; PET; myocardial fibrosis