Inflammation and chemerin in colorectal cancer

• Published in: Tumor biology Vol. 37; no. 5; pp. 6337 - 6342
• Main Authors: Erdogan, Serpil, Yilmaz, Fatma Meric, Yazici, Ozan, Yozgat, Ahmet, Sezer, Sevilay, Ozdemir, Nuriye, Uysal, Sema, Purnak, Tugrul, Sendur, Mehmet Ali, Ozaslan, Ersan
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.05.2016; Springer Nature B.V
• Subjects: Adiponectin - biosynthesis; Adiponectin - blood; Adult; Aged; Biomedical and Life Sciences; Biomedicine; Blood Sedimentation; C-Reactive Protein - genetics; Cancer Research; Chemokines - biosynthesis; Chemokines - blood; Chemokines - genetics; Colorectal cancer; Colorectal Neoplasms - blood; Colorectal Neoplasms - genetics; Colorectal Neoplasms - pathology; Erythrocytes; Female; Fibrinogen - genetics; Fibrinogen - metabolism; Humans; Inflammation; Inflammation - blood; Inflammation - genetics; Inflammation - pathology; Intercellular Signaling Peptides and Proteins - biosynthesis; Intercellular Signaling Peptides and Proteins - blood; Intercellular Signaling Peptides and Proteins - genetics; Male; Middle Aged; Original Article; Proteins; Risk Factors; Serpins - blood; Serpins - genetics; Tumor Microenvironment - genetics; Chemerin; Inflammation; C-reactive protein; Erythrocyte sedimentation rate; Colorectal cancer; Fibrinogen

Chemerin is expressed mainly in the adipose tissue. It is an agonist of chemokine-like receptor-1, which is expressed by the immune system cells. Chemerin stimulates the chemotaxis of the immune system cells, and this indicates the function of chemerin and chemokine-like receptor-1 in the immune res...