Anti-IL-1 treatment in familial Mediterranean fever and related amyloidosis

• Published in: Clinical rheumatology Vol. 35; no. 2; pp. 441 - 446
• Main Authors: Özçakar, Z. Birsin, Özdel, Semanur, Yılmaz, Songül, Kurt-Şükür, E. Didem, Ekim, Mesiha, Yalçınkaya, Fatoş
• Format: Journal Article
• Language: English
• Published: London Springer London 01.02.2016; Springer Nature B.V
• Subjects: Adolescent; Amyloidosis - drug therapy; Amyloidosis - etiology; Antibodies, Monoclonal - therapeutic use; Child; Colchicine - therapeutic use; Drug Resistance; Familial Mediterranean Fever - complications; Familial Mediterranean Fever - drug therapy; Female; Humans; Interleukin 1 Receptor Antagonist Protein - therapeutic use; Male; Medicine; Medicine & Public Health; Original Article; Retrospective Studies; Rheumatology; Young Adult; Amyloidosis; Familial Mediterranean fever; Treatment; Canakinumab; Anakinra

Colchicine is the standard treatment in familial Mediterranean fever (FMF) patients. New treatment strategies are needed in FMF patients who were unresponsive to colchicine therapy or who had developed amyloidosis. The aim of this study was to present clinical-laboratory features and treatment respo...