Repeated Spiral Drawings in Essential Tremor: a Possible Limb-Based Measure of Motor Learning

• Published in: Cerebellum (London, England) Vol. 18; no. 2; pp. 178 - 187
• Main Authors: Kim, Christine Y., Luo, Lan, Yu, Qiping, Mirallave, Ana, Saunders-Pullman, Rachel, Lipton, Richard B., Louis, Elan D., Pullman, Seth L.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2019; Springer Nature B.V
• Subjects: Aged, 80 and over; Biomechanical Phenomena; Biomedical and Life Sciences; Biomedicine; Cerebellum; Clinical trials; Cohort Studies; Computer applications; Diagnosis, Computer-Assisted; Essential Tremor - diagnosis; Essential Tremor - physiopathology; Female; Humans; Learning - physiology; Learning Disabilities - diagnosis; Learning Disabilities - etiology; Learning Disabilities - physiopathology; Male; Motor skill learning; Motor Skills - physiology; Neurobiology; Neurology; Neurosciences; Original Paper; Severity of Illness Index; Tremor; Upper Extremity - physiopathology; Cerebellum; Essential tremor; Motor learning; Computerized spiral analysis; Movement disorders
• ISSN: 1473-4222; 1473-4230; 1473-4230
• DOI: 10.1007/s12311-018-0974-x

To investigate changes in tremor severity over repeated spiral drawings to assess whether learning deficits can be evaluated directly in a limb in essential tremor (ET). A motor learning deficit in ET, possibly mediated by cerebellar pathways, has been established in eye-blink conditioning studies,...