Effects of quercetin loaded nanostructured lipid carriers on the paraquat-induced toxicity in human lymphocytes

• Published in: Pesticide biochemistry and physiology Vol. 167; p. 104586
• Main Authors: Ahmadian, Elham, Eftekhari, Aziz, Kavetskyy, Taras, Khosroushahi, Ahmad Yari, Turksoy, Vugar Ali, Khalilov, Rovshan
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.07.2020
• Subjects: antioxidant activity; Blood lymphocytes; cell death; centrifugation; drugs; encapsulation; Environmental pollutant; ficoll; gene expression; Herbicide; humans; light scattering; lipid peroxidation; lipids; lymphocytes; lysosomes; membrane potential; mitochondrial membrane; Nanostructured lipid carriers; paraquat; poisoning; pollutants; Quercetin; reactive oxygen species; therapeutics; toxicity; transmission electron microscopy; viability; Nanostructured lipid carriers; Blood lymphocytes; Environmental pollutant; Herbicide; Quercetin

Paraquat (PQ) as a herbicide and an environmental pollutant with increasing importance due to its toxicity to humans and animals. This study aimed to evaluate the protective and antioxidant activity of quercetin loaded Nanostructured Lipid Carriers (QNLC) against toxicity induced by PQ. Blood lympho...