A pilot study of salivary N-glycome in HBV-induced chronic hepatitis, cirrhosis, and hepatocellular carcinoma

• Published in: Glycoconjugate journal Vol. 34; no. 4; pp. 523 - 535
• Main Authors: Qin, Yannan, Zhong, Yaogang, Ma, Tianran, Zhang, Jiaxu, Yang, Ganglong, Guan, Feng, Li, Zheng, Li, Baozhen
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.08.2017; Springer Nature B.V
• Subjects: Adult; Aged; Biochemistry; Biomedical and Life Sciences; Carcinoma, Hepatocellular - metabolism; Carcinoma, Hepatocellular - virology; Case-Control Studies; Chronic illnesses; Cirrhosis; Death; Female; Glycoproteins; Glycosylation; Hepatitis; Hepatitis B; Hepatitis B virus - physiology; Hepatitis, Chronic - metabolism; Hepatitis, Chronic - virology; Hepatocellular carcinoma; Hepatology; Humans; Life Sciences; Liver cancer; Liver cirrhosis; Liver Cirrhosis - metabolism; Liver Cirrhosis - virology; Liver diseases; Liver Neoplasms - metabolism; Liver Neoplasms - virology; Male; Metabolome; Middle Aged; N-glycans; Original Article; Pathology; Pilot Projects; Polysaccharides; Polysaccharides - metabolism; Saliva; Saliva - metabolism; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Cirrhosis; Hepatocellular carcinoma; N-glycan; MALDI-TOF/TOF-MS; Saliva; HBV

Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV), which can lead to chronic liver disease and put people at high risk of death from cirrhosis of the liver and liver cancer. However, little is known about the correlation of salivary N-linked glycans...