Radiosynthesis and First-In-Human PET/MRI Evaluation with Clinical-Grade [18F]FTC-146 - Shen, Bin; Park, Jun Hyung; Hjørnevik, Trine; Cipriano, Peter W.; Yoon, Daehyun; Gulaka, Praveen K.; Holly, Dawn; Behera, Deepak; Avery, Bonnie A.; Gambhir, Sanjiv S.; McCurdy, Christopher R.; Biswal, Sandip; et al. (Molecular imaging and biology, 2017)
Keywords: Adult; Ambient temperature; Azepines - chemical synthesis; Azepines - chemistry; Azepines - pharmacokinetics; Benzothiazoles - chemical synthesis; Benzothiazoles - chemistry; Benzothiazoles - pharmacokinetics; Blood-brain barrier; Brain; Cortical bone; Ethanol; Evaluation; Female; Fluorides; Humans; Imaging; In vivo methods and tests; Lungs; Magnetic Resonance Imaging; Male; Medicine; Medicine & Public Health; Neuroimaging; Neurological diseases; NMR; Nuclear magnetic resonance; Organs; Pancreas; Positron emission; Positron emission tomography; Quality control; Radioactivity; Radiochemistry; Radioisotopes; Radiology; Receptors; Research Article; Selectivity; Sodium chloride; Spleen; Thyroid; Tissue Distribution; Tomography; Automated radiosynthesis; Clinical; sigma-1 receptor; [18F]FTC-146; PET/MRI; Radiopharmaceuticals