Cytochrome P450-based metabolic insecticide resistance in Anopheles and Aedes mosquito vectors: Muddying the waters

• Published in: Pesticide biochemistry and physiology Vol. 170; p. 104666
• Main Authors: Vontas, John, Katsavou, Eva, Mavridis, Konstantinos
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.11.2020
• Subjects: Aedes; allelic variation; Anopheles; Anoplehes; catalytic activity; cross resistance; CYP; cytochrome P-450; Dengue; Detoxification; diagnostic techniques; Diagnostics; insecticide resistance; Malaria; physiology; resistance management; Malaria; Diagnostics; Dengue; Detoxification; Anoplehes; CYP; Aedes

Despite the substantial progress achieved in the characterization of cytochrome P450 (CYP) -based resistance mechanisms in mosquitoes, a number of questions remain unanswered. These include: (i) the regulation and physiology of resistance conferring CYPs; (ii) the actual contribution of CYPs in resi...