A Plant-Based Dietary Supplement Exhibits Significant Effects on Markers of Oxidative Stress, Inflammation, and Immune Response in Subjects Recovering from Respiratory Viral Infection: A Randomized, Double-Blind Clinical Study Using Vitamin C as a Positive Control - Fink, Bruno; Hunter, John M.; Pietrzkowski, Zbigniew; Fink, Richard; Brunssen, Coy; Morawietz, Henning; Nemzer, Boris (International journal of molecular sciences, 2025)
Keywords: Adult; Antioxidants; Ascorbic Acid - administration & dosage; Ascorbic Acid - pharmacology; Ascorbic Acid - therapeutic use; Bioavailability; Biomarkers - blood; Chemokines; COVID-19; COVID-19 - immunology; COVID-19 Drug Treatment; Cytokines; Dietary Supplements; Double-Blind Method; Enzymes; Female; Humans; Immune response; Infections; Inflammation; Inflammation - drug therapy; Influenza; Male; Metabolic syndrome; Middle Aged; Neutrophils; Nitric oxide; Overweight; Oxidative Stress - drug effects; Reactive oxygen species; Reactive Oxygen Species - metabolism; Respiratory distress syndrome; Respiratory syncytial virus; Respiratory Tract Infections - immunology; SARS-CoV-2; Viral infections; Viruses; Vitamin C; influenza; phagocytic NADPH oxidase; uncoupled iNOS; viral insult; endothelial dysfunction; COVID-19; cellular metabolic activity (CMA); circulating NOHb; seasonal virus; ROS; flu season; FMD; inducible nitric oxide synthase (iNOS); dietary supplement PB-blend