Synthesis of potential drug metabolites by a modified Udenfriend reaction - Slavik, Roger; Peters, Jens-Uwe; Giger, Rudolf; Bürkler, Markus; Bald, Eric (Tetrahedron letters, 2011)
Keywords: Accessibility; Aromatic hydroxylation; Biomedical materials; Biomimetic oxidation; chemical structure; Chemistry; Chemistry, Organic; chlorpromazine; derivatization; Diltiazem; Drug discovery; Drugs; hydroxylation; In vivo testing; In vivo tests; Metabolites; oxidation; Physical Sciences; propranolol; Science & Technology; Synthesis (chemistry); Aromatic hydroxylation; Drug discovery; Metabolites; Biomimetic oxidation; CLOZAPINE; RAT; DEMETHYLATION; MIST; HYDROGEN-PEROXIDE; FENTON REAGENT; MODEL; SELECTIVITY