The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren’s syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial

• Published in: Clinical rheumatology Vol. 38; no. 3; pp. 657 - 664
• Main Authors: Liu, Xia, Li, Xiaomei, Li, Xiangpei, Li, Zhijun, Zhao, Dongbao, Liu, Shengyun, Zhang, Miaojia, Zhang, Fengxiao, Zhu, Ping, Chen, Jinwei, Wei, Wei, Lin, Bing, Zhou, Yingbo, Chen, Jing, Pang, Yafei, Zhang, Lei, Sun, Xiaoxuan, Yu, Zhibo, Jia, Yun, Wang, Jia, Sun, Wenwen, Chiu, Frank, Pang, Liping, Wang, Guochun
• Format: Journal Article
• Language: English
• Published: London Springer London 01.03.2019; Springer Nature B.V
• Subjects: Adult; Clinical trials; Diarrhea - chemically induced; Double-Blind Method; Erythrocyte sedimentation rate; Fatigue; Female; Glucosides; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Nose; Original Article; Paeonia; Pain; Pain Measurement; Patients; Pharynx; Phytotherapy; Plant Extracts - therapeutic use; Plant Roots; Rheumatology; Salivary Elimination; Severity of Illness Index; Sjogren's syndrome; Sjogren's Syndrome - drug therapy; Sjogren's Syndrome - physiopathology; Skin; Treatment Outcome; Vagina; Visual Analog Scale; Total glucosides of peony; Sjögren’s syndrome; Randomized controlled trials

To evaluate the efficacy and safety of total glucosides of peony (TGP) in adults with primary Sjögren’s syndrome (pSS). A multi-center, randomized, double-blinded, placebo-controlled study was conducted between March 2012 and July 2014 at ten Chinese hospitals. In total, 320 pSS patients—classified...