Activity of propolis compounds as potential MMP1 and MMP2 inhibitors by in silico studies in wound healing application

• Published in: Journal of pharmacy & pharmacognosy research Vol. 12; no. 2; pp. 264 - 285
• Main Authors: Arda, Adzani Gaisani, Syaifie, Putri Hawa, Ramadhan, Donny, Jauhar, Muhammad Miftah, Nugroho, Dwi Wahyu, Kaswati, Nofa Mardia Ningsih, Noviyanto, Alfian, Safihtri, Mega, Rochman, Nurul Taufiqu, Andrianto, Dimas, Mardliyati, Etik
• Format: Journal Article
• Language: English
• Published: GarVal Editorial Ltda 01.03.2024
• Subjects: matrix metalloproteinases; molecular docking simulation; molecular dynamics simulation; propolis; wound healing

Context: Matrix metalloproteinases (MMPs) play a critical role in wound healing, with higher levels seen in chronic wounds, delaying healing. Since ancient times, propolis has been widely used for traditional wound healing. However, there is still limited research on MMP1 and MMP12. Aims: To evaluat...