Anandamide and other N‐acylethanolamines in human tumors

• Published in: Lipids Vol. 37; no. 9; pp. 907 - 912
• Main Authors: Schmid, Patricia C., Wold, Lester E., Krebsbach, Randy J., Berdyshev, Evgueni V., Schmid, Harald H. O.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer‐Verlag 01.09.2002; Springer Nature B.V
• Subjects: Arachidonic Acids - analysis; Arachidonic Acids - metabolism; Cells; Endocannabinoids; Ethanolamines - analysis; Ethanolamines - metabolism; Humans; Neoplasms - chemistry; Neoplasms - metabolism; Polyunsaturated Alkamides; Tissue Extracts - chemistry; Tissue Extracts - metabolism; Tumor Cells, Cultured; Tumors

Long‐chain N‐acylethanolamines (NAE), including the endocannabinoid, anandamide, accumulate in mammalian tissues under a variety of pathological conditions. They have also been shown to inhibit the growth of various cancer cell lines in vitro. Here, we report the presence, in widely differing amount...