Anti‐inflammatory properties of an aldehydes‐enriched fraction of grapefruit essential oil

• Published in: Journal of food science Vol. 88; no. 3; pp. 1172 - 1187
• Main Authors: Nikolic, Dragana, Bosco, Liana, Moschetti, Marta, Tinnirello, Vincenza, Pucci, Marzia, Corleone, Valeria, Raimondo, Stefania, Alessandro, Riccardo, Fontana, Simona
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.03.2023
• Subjects: Alcohols; Aldehydes; Aldehydes - pharmacology; Anti-Inflammatory Agents - pharmacology; Anti-Inflammatory Agents - therapeutic use; citral; Citrus fruits; Citrus paradisi; Cytokines; Diseases; essential oil; Essential oils; Esters; Flavonoids; Food; Fruits; Functional foods & nutraceuticals; Gene expression; Grapefruit; Inflammation; Inflammation - drug therapy; Inflammation - prevention & control; Interleukin 6; Lipopolysaccharides; Macrophages; Monoterpenes; nutraceuticals; Oils & fats; Oils, Volatile - pharmacology; Olfactory properties; Phenols; Sesquiterpenes; spray‐dry; aldehydes; citral; inflammation; nutraceuticals; spray-dry; Citrus paradisi; essential oil

Chronic inflammation is linked to the development of numerous diseases and is accompanied by increased cytokine secretion. Macrophages provide a first line of defense against pathogens that under inflammatory stimuli release pro‐inflammatory cytokines. The essential oil (EO) fractions obtained from...