S100A14 promotes the growth and metastasis of hepatocellular carcinoma

• Published in: Asian Pacific journal of cancer prevention : APJCP Vol. 14; no. 6; pp. 3831 - 3836
• Main Authors: Zhao, Fu-Tao, Jia, Zhan-Sheng, Yang, Qun, Song, Le, Jiang, Xiao-Jing
• Format: Journal Article
• Language: English
• Published: Thailand 01.01.2013
• Subjects: Adult; Aged; Animals; Biomarkers, Tumor - genetics; Biomarkers, Tumor - metabolism; Blotting, Western; Calcium-Binding Proteins - genetics; Calcium-Binding Proteins - metabolism; Carcinoma, Hepatocellular - metabolism; Carcinoma, Hepatocellular - mortality; Carcinoma, Hepatocellular - secondary; Cell Movement; Cell Proliferation; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Liver Neoplasms - metabolism; Liver Neoplasms - mortality; Liver Neoplasms - pathology; Lymphatic Metastasis; Male; Mice; Mice, SCID; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Recurrence, Local - metabolism; Neoplasm Recurrence, Local - mortality; Neoplasm Recurrence, Local - pathology; Prognosis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - genetics; Survival Rate; Tumor Cells, Cultured; Wound Healing; Young Adult

S100A14 has recently been implicated in the progress of several types of cancers. This study aimed to investigate the clinical significance and possible mechanisms of action of S100A14 in the invasion and metastasis of hepatocellular carcinoma (HCC). S100A14 expression in HCC was detected at mRNA an...