Approximate confidence intervals for the weighted kappa coefficient of a binary diagnostic test subject to a case-control design

• Published in: Journal of statistical computation and simulation Vol. 87; no. 3; pp. 530 - 545
• Main Authors: Roldán-Nofuentes, J. A., Amro, R. M.
• Format: Journal Article
• Language: English
• Published: Abingdon Taylor & Francis 11.02.2017; Taylor & Francis Ltd
• Subjects: 6207; Binary diagnostic test; case-control design; Coefficients; Confidence intervals; Correlation analysis; Design analysis; Diagnostic systems; Diagnostic tests; Metric system; Samples; Sensitivity; Statistical analysis; Statistical methods; weighted kappa coefficient

Case-control design to assess the accuracy of a binary diagnostic test (BDT) is very frequent in clinical practice. This design consists of applying the diagnostic test to all of the individuals in a sample of those who have the disease and in another sample of those who do not have the disease. The...