The Magnetic Resonance Imaging in Active Surveillance (MRIAS) Trial: Use of Baseline Multiparametric Magnetic Resonance Imaging and Saturation Biopsy to Reduce the Frequency of Surveillance Prostate Biopsies

• Published in: The Journal of urology Vol. 203; no. 5; pp. 910 - 917
• Main Authors: Amin, Amer, Scheltema, Matthijs J., Shnier, Ron, Blazevski, Alexandar, Moses, Daniel, Cusick, Thomas, Siriwardena, Amila, Yuen, Brian, van Leeuwen, Pim J., Haynes, Anne Maree, Matthews, Jayne, Brenner, Phillip, O'Neill, Gordon, Yuen, Carlo, Delprado, Warick, Stricker, Phillip, Thompson, James
• Format: Journal Article
• Language: English
• Published: United States 01.05.2020
• Subjects: Aged; Biopsy - methods; Biopsy - statistics & numerical data; Disease Progression; Early Detection of Cancer - methods; Follow-Up Studies; Humans; Male; Middle Aged; Multiparametric Magnetic Resonance Imaging - methods; Multiparametric Magnetic Resonance Imaging - statistics & numerical data; Neoplasm Staging - methods; Predictive Value of Tests; Prognosis; Prospective Studies; Prostate - pathology; Prostate-Specific Antigen - metabolism; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - metabolism; Time Factors; multiparametric magnetic resonance imaging; watchful waiting; prostatic neoplasms

Prospective studies are lacking in assessing the diagnostic utility of serial multiparametric magnetic resonance imaging to predict biopsy proven progression to clinically significant prostate cancer in men on active surveillance, as well as the oncologic safety of baseline magnetic resonance imagin...