Urate promotes SNCA/α-synuclein clearance via regulating mTOR-dependent macroautophagy - Sheng, Yu-Lan; Chen, Xing; Hou, Xiao-Ou; Yuan, Xin; Yuan, Bao-Shi; Yuan, Yu-Qing; Zhang, Qi-Lin; Cao, Xian; Liu, Chun-Feng; Luo, Wei-Feng; Hu, Li-Fang (Experimental neurology, 2017)
Keywords: alpha-Synuclein - metabolism; Animals; Autophagy - drug effects; Autophagy - physiology; Cell Survival - drug effects; Cell Survival - physiology; Dose-Response Relationship, Drug; Humans; Macroautophagy; Male; Metabolic Clearance Rate - drug effects; Metabolic Clearance Rate - physiology; Mice; Mice, Inbred C57BL; Mice, Transgenic; mTOR; Parkinson's disease; PC12 Cells; Pilot Projects; Rats; SNCA/α-synuclein; TOR Serine-Threonine Kinases - physiology; Urate; Uric Acid - pharmacology; mTOR; SNCA/α-synuclein; Parkinson's disease; Macroautophagy; Urate