Multivariate classification of autism spectrum disorder using frequency-specific resting-state functional connectivity—A multi-center study

• Published in: Progress in neuro-psychopharmacology & biological psychiatry Vol. 64; pp. 1 - 9
• Main Authors: Chen, Heng, Duan, Xujun, Liu, Feng, Lu, Fengmei, Ma, Xujing, Zhang, Youxue, Uddin, Lucina Q., Chen, Huafu
• Format: Journal Article
• Language: English
• Published: England 04.01.2016
• Subjects: Adolescent; Autism Spectrum Disorder - classification; Autism Spectrum Disorder - physiopathology; Brain - physiopathology; Brain Mapping; Child; Data Interpretation, Statistical; Databases, Factual; Female; Head Movements; Humans; Magnetic Resonance Imaging - methods; Male; Multivariate Analysis; Neural Pathways - physiopathology; Rest; Severity of Illness Index; Support Vector Machine; Functional connectivity; Slow-4; Multivariate pattern analysis; Autism spectrum disorder

Resting-state functional magnetic resonance imaging studies examining low frequency fluctuations (0.01-0.08 Hz) have revealed atypical whole brain functional connectivity patterns in adolescents with autism spectrum disorder (ASD), and these atypical patterns can be used to discriminate individuals...