Cross‐sectional evaluation of gut microbial–host cometabolites in patients with chronic pancreatitis

• Published in: Journal of digestive diseases Vol. 24; no. 1; pp. 51 - 59
• Main Authors: Xu, Jia Jia, Meng, Yu Ting, Zou, Wen Bin, Zhao, Jiu Long, Fang, Xue, Zhang, Yao, Zhou, Wei, Zhang, Ling, Wang, Kai Xuan, Hu, Liang Hao, Liao, Zhuan, Zhou, Chun Hua, Zou, Duo Wu
• Format: Journal Article
• Language: English
• Published: Melbourne Wiley Publishing Asia Pty Ltd 01.01.2023; Wiley Subscription Services, Inc
• Subjects: Abundance; Bacteria; Bifidobacterium; chronic pancreatitis; Citric acid; Correlation analysis; Cross-Sectional Studies; Digestive system; Feces; Feces - microbiology; Gas chromatography; Gastrointestinal Microbiome; Gastrointestinal tract; gut metabolites; gut microbial–host cometabolites; Humans; Intestinal microflora; Mass spectroscopy; Metabolites; Metabolome; Microbiomes; Microbiota; Pancreatitis; Pancreatitis, Chronic; RNA, Ribosomal, 16S - genetics; rRNA 16S; Bifidobacterium; chronic pancreatitis; gut microbial-host cometabolites; metabolome; gut metabolites

Objectives Gut bacteria facilitate nutrient metabolism and generate small molecules that form part of the broader “metabolome”. It is unclear whether these metabolites are disturbed in chronic pancreatitis (CP). This study aimed to evaluate the gut microbial–host cometabolites and their relationship...