Role of Diastolic Stress Testing in the Evaluation for Heart Failure With Preserved Ejection Fraction: A Simultaneous Invasive-Echocardiographic Study

• Published in: Circulation (New York, N.Y.) Vol. 135; no. 9; pp. 825 - 838
• Main Authors: Obokata, Masaru, Kane, Garvan C., Reddy, Yogesh N. V., Olson, Thomas P., Melenovsky, Vojtech, Borlaug, Barry A.
• Format: Journal Article
• Language: English
• Published: United States by the American College of Cardiology Foundation and the American Heart Association, Inc 28.02.2017
• Subjects: Aged; Aged, 80 and over; Echocardiography; Exercise Test; Female; Heart Failure - diagnosis; Heart Failure - diagnostic imaging; Hemodynamics; Humans; Male; Middle Aged; Natriuretic Peptide, Brain - analysis; Peptide Fragments - analysis; Prospective Studies; Stroke Volume - physiology; Ventricular Function, Left - physiology; heart failure; diagnosis; exercise; exercise test

BACKGROUND:Diagnosis of heart failure with preserved ejection fraction (HFpEF) is challenging and relies largely on demonstration of elevated cardiac filling pressures (pulmonary capillary wedge pressure). Current guidelines recommend use of natriuretic peptides (N-terminal pro-B type natriuretic pe...