The TH1 phenotype of follicular helper T cells indicates an IFN-γ–associated immune dysregulation in patients with CD21low common variable immunodeficiency - Unger, Susanne; Seidl, Maximilian; van Schouwenburg, Pauline; Rakhmanov, Mirzokhid; Bulashevska, Alla; Frede, Natalie; Grimbacher, Bodo; Pfeiffer, Jens; Schrenk, Klaudia; Munoz, Luis; Hanitsch, Leif; Stumpf, Ina; et al. (Journal of allergy and clinical immunology, 2018)
Keywords: Autoimmunity; Bacterial infections; CCR6 protein; CD21low B cells; CD4 antigen; Common variable immunodeficiency; CXCR3 protein; Flow cytometry; Follicular helper T cells; Gene expression; Genotype & phenotype; germinal center; Helper cells; Histology; HIV; Human immunodeficiency virus; IFN-γ; Immunoglobulins; Immunological memory; Lung diseases; Lupus; Lymph nodes; Lymphatic system; Lymphocytes B; Lymphocytes T; Lymphoma; Memory cells; Morbidity; Mutation; Normal distribution; Peripheral blood; Phenotypes; T-bet; Ultrasonic imaging; γ-Interferon; Germany; CVIDio; CD21low B cells; smB; Follicular helper T cells; common variable immunodeficiency; germinal center; NFKB; T-bet; CVIDc; CT; CVID; IFN-γ; STAT; FcRL4; SLO; TFH; HCV; GC; HD; memCD4; cTFH