Comparative study of neuropeptide signaling systems in Hemiptera

• Published in: Insect science Vol. 30; no. 3; pp. 705 - 724
• Main Authors: Gao, Han, Li, Yanxiao, Zhang, Hui, Wang, Suisui, Feng, Fan, Tang, Jing, Li, Bin
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.06.2023
• Subjects: Comparative studies; Corazonin protein; D. vitifoliae; G protein-coupled receptors; GPCR; Hemiptera; Insects; neuropeptide; Neuropeptide g; Neuropeptides; Peptides; Phylogeny; Receptors; Signalling systems; Sternorrhyncha; GPCR; Hemiptera; neuropeptide; D. vitifoliae
• ISSN: 1672-9609; 1744-7917
• DOI: 10.1111/1744-7917.13120

Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form an ancient signaling system, there is still a great deal of variety in neuropeptides and their receptors among different species within the same order. Neuropeptides and their receptors have been documented in many hemipteran insects, but the differences among them have been poorly characterized. Commercial grapevines worldwide are plagued by the bug Daktulosphaira vitifoliae (Hemiptera: Sternorrhyncha). Here, 33 neuropeptide precursors and 48 putative neuropeptide G protein‐coupled receptor (GPCR) genes were identified in D. vitifoliae. Their expression profiles at the probe and feeding stages reflected potential regulatory roles in probe behavior. By comparison, we found that the Releasing Hormone‐Related Peptides (GnRHs) system of Sternorrhyncha was differentiated from those of the other 2 suborders in Hemiptera. Independent secondary losses of the adipokinetic hormone/corazonin‐related peptide receptor (ACP) and corazonin (CRZ) occurred during the evolution of Sternorrhyncha. Additionally, we discovered that the neuropeptide signaling systems of Sternorrhyncha were very different from those of Heteroptera and Auchenorrhyncha, which was consistent with Sternorrhyncha's phylogenetic position at the base of the order. This research provides more knowledge on neuropeptide systems and sets the groundwork for the creation of novel D. vitifoliae management strategies that specifically target these signaling pathways. Graphical As the bottom phylogenetic position of Hemiptera, Sternorrhyncha has a simplified neuropeptide signaling system than Heteroptera and Auchenorrhyncha. The simplified survival environment for Sternorrhyncha means they can suffice with fewer neuropeptide signaling systems.