Inspection time: a neuropsychophysiological test for measuring the functional integrity of the cholinergic system

• Published in: Medical hypotheses Vol. 57; no. 6; pp. 759 - 760
• Main Authors: Nathan, P.J., Stough, C.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.12.2001; Elsevier
• Subjects: Alzheimer Disease - physiopathology; Alzheimer Disease - psychology; Biological and medical sciences; Biomarkers; Cholinergic Fibers - physiology; Humans; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Mental Processes - physiology; Nervous system; Neuropsychological Tests; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Time Factors; Tropical medicine; Human; Neuropsychological test; Inspection; Nervous system; Exploration; Time; Technique; Discussion; Cholinergic pathway

Inspection time (IT) is a measure of the speed of early information processing, demonstrating reliable correlation with psychometric intelligence. We now provide evidence that it may serve as a marker for the integrity of the cholinergic system. Cholinergic agonists improve and antagonists impair IT...