Biological variation of high sensitive Troponin T in stable heart failure patients with ischemic or dilated cardiomyopathy

• Published in: Clinical research in cardiology Vol. 100; no. 8; pp. 633 - 640
• Main Authors: Frankenstein, Lutz, Remppis, Andrew, Giannitis, Evangelos, Frankenstein, Joerdis, Hess, Georg, Zdunek, Dietmar, Doesch, Andreas, Zugck, Christian, Katus, Hugo A.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.08.2011; Springer Nature B.V
• Subjects: Aged; Biomarkers - blood; Cardiology; Cardiomyopathy, Dilated - blood; Chronic Disease; Cohort Studies; Female; Follow-Up Studies; Heart Failure - blood; Humans; Luminescent Measurements; Male; Medicine; Medicine & Public Health; Middle Aged; Myocardial Ischemia - blood; Original Paper; Prospective Studies; Troponin T - blood; High-sensitivity assay; Reference change value; Biovariability; High sensitive Troponin

Introduction High sensitive Troponin (hsTn) assays enable detection of minimal marker elevation in heart failure patients previously deemed Troponin negative. Biovariability, reference change values (RCV), and index of individuality (II) have not been previously described for hsTnT although serial t...