Effect of upright tilt on ventricular/vascular coupling in chronically instrumented primates

• Published in: The American journal of physiology Vol. 265; no. 1 Pt 2; p. H244
• Main Authors: Tran, C C, Latham, R D, Self, D A, Fanton, J W, White, C D, Owens, R W
• Format: Journal Article
• Language: English
• Published: United States 01.07.1993
• Subjects: Animals; Blood Vessels - physiology; Consciousness; Hemodynamics - drug effects; Ketamine - pharmacology; Papio; Posture; Supination; Ventricular Function, Left; NASA Discipline Cardiopulmonary; NASA Program Space Physiology and Countermeasures; NASA Discipline Number 14-10; Non-NASA Center

Studies of the hydraulic loading conditions on the heart in humans, especially pulsatile load, have primarily been limited to the supine state. Therefore, we have chosen a nonhuman primate model, the baboon, to assess left ventricular/vascular coupling in both supine and upright positions. Primate s...