Spray-Drying of Hydroxypropyl β-Cyclodextrin Microcapsules for Co-Encapsulation of Resveratrol and Piperine with Enhanced Solubility

• Published in: Crystals (Basel) Vol. 12; no. 5; p. 596
• Main Authors: Yang, Xing, Shen, Jian, Liu, Jia, Yang, Yuxin, Hu, Anna, Ren, Na, Cheng, Zeneng, Liu, Wenjie
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.05.2022
• Subjects: Aluminum; antioxidant; Antioxidants; Bioavailability; Cyclodextrins; Drying; Efficiency; Encapsulation; hydroxypropyl β-cyclodextrin; Inclusion complexes; Ingredients; Microencapsulation; Particle size; piperine; resveratrol; Scanning electron microscopy; Scavenging; Solubility; Spectrum analysis; spray-drying; Strong interactions (field theory); China; Japan; Germany

The synergistic therapeutic benefits of resveratrol (RES) and piperine (PIP) have been proven for the treatment of various diseases. This study reports, for the first time, spray-drying of hydroxypropyl β-cyclodextrin (HP-β-CD) microcapsules for combined delivery of resveratrol and piperine. Phase s...