Green Tea Seed Oil Suppressed Aβ1–42-Induced Behavioral and Cognitive Deficit via the Aβ-Related Akt Pathway

• Published in: International journal of molecular sciences Vol. 20; no. 8; p. 1865
• Main Authors: Kim, Jong Min, Park, Seon Kyeong, Kang, Jin Yong, Park, Su Bin, Yoo, Seul Ki, Han, Hye Ju, Cho, Kyoung Hwan, Kim, Jong Cheol, Heo, Ho Jin
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 15.04.2019; MDPI
• Subjects: AKT protein; amyloid β; Anti-inflammatory agents; Antioxidants; Aβ-related Akt pathway; Brain; Dietary fiber; Disease; Functional foods & nutraceuticals; Green tea; green tea seed oil; Inflammation; Ionic mobility; Liquid chromatography; Long term memory; Mass spectrometry; Mass spectroscopy; Memory; neuroprotective effect; Oilseeds; Oxidative stress; Peptides; Pheochromocytoma cells; Physiology; Polyphenols; Probiotics; Proteins; Quadrupoles; Seeds; Spatial discrimination learning; Spatial memory; Spices; Tea; Vitamins

The aim of this study was to investigate the availability of seeds, one of the byproducts of green tea, and evaluate the physiological activity of seed oil. The ameliorating effect of green tea seed oil (GTO) was evaluated on H2O2-induced PC12 cells and amyloid beta (Aβ)1–42-induced ICR mice. GTO sh...