Transcriptional processes: Models and inference

• Published in: Journal of bioinformatics and computational biology Vol. 16; no. 5; p. 1850023
• Main Authors: Shetty, Keerthi S, B, Annappa
• Format: Journal Article
• Language: English
• Published: Singapore 01.10.2018
• Subjects: mass action kinetics; multistep promoter model; time-series data; Parameter inference

Many biochemical events involve multistep reactions. One of the most important biological processes that involve multistep reaction is the transcriptional process. Models for multistep reaction necessarily need multiple states and it is a challenge to compute model parameters that best agree with ex...