A technique to reduce low dose region for craniospinal irradiation (CSI) with RapidArc and its dosimetric comparison with 3D conformal technique (3DCRT)

• Published in: Journal of cancer research and therapeutics Vol. 11; no. 2; pp. 488 - 491
• Main Authors: Srivastava, Roopam, Saini, Gagan, Sharma, Pramod Kumar, Chomal, Manish, Aagarwal, Anchal, Nangia, Sapna, Garg, Madhur
• Format: Journal Article
• Language: English
• Published: India Medknow Publications & Media Pvt. Ltd 01.04.2015
• Subjects: Craniospinal Irradiation - methods; Dosimetry; Heart; Humans; Lungs; Radiation therapy; Radiometry - methods; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted - methods; Radiotherapy, Conformal - methods; Radiotherapy, Intensity-Modulated - methods; Retrospective Studies
• DOI: 10.4103/0973-1482.144556
• ISSN: 0973-1482

We proposed a method to reduce the volume of normal tissues irradiated by low doses in patients receiving CSI with RapidArc (RA) using Avoidance-Sector technique (RA+AS) and to compare its dosimetric implications with RA using full-arc (RA+FA) and 3D conformal technique (3DCRT). Four patients of CSI were retrospectively planned with 3DCRT, RA+FA, and RA+AS. Conformity-Index (CI), Homogeneity-Index (HI), and Paddick Gradient-Index (GI) were calculated. Quantitative evaluation was done using DVH analysis for PTVs and OARs. When compared with 3DCRT, GI, CI, and HI were favorable to RA based techniques. In comparison with 3DCRT the doses to OARs were lower with RA+AS with the difference being statistically significant in most instances. RA+AS significantly decreases the dose to OARs and their volumes receiving low doses in comparison with RA+FA and 3DCRT.