In vivo Raman spectroscopic identification of premalignant lesions in oral buccal mucosa

• Published in: Journal of biomedical optics Vol. 17; no. 10; pp. 1050021 - 1-105002-2
• Main Authors: Singh, S. P., Deshmukh, Atul, Chaturvedi, Pankaj, Murali Krishna, C.
• Format: Journal Article
• Language: English
• Published: United States 01.10.2012
• Subjects: Adult; Algorithms; Cancer; Carcinoma, Squamous Cell - chemistry; Carcinoma, Squamous Cell - pathology; Case-Control Studies; Fiber optics; Habits; Humans; Lesions; Middle Aged; Mouth Mucosa - chemistry; Mouth Mucosa - pathology; Mouth Neoplasms - chemistry; Mouth Neoplasms - diagnosis; Mouth Neoplasms - pathology; Optical fibers; Precancerous Conditions - chemistry; Precancerous Conditions - diagnosis; Precancerous Conditions - pathology; Principal Component Analysis; Smoking - pathology; Spectra; Spectroscopy; Spectrum Analysis, Raman - methods; Tobacco; Tobacco, Smokeless

Cancers of oral cavities are one of the most common malignancies in India and other south-Asian countries. Tobacco habits are the main etiological factors for oral cancer. Identification of premalignant lesions is required for improving survival rates related to oral cancer. Optical spectroscopy met...