The Effect of Age and Prolonged Cold Ischemia Times on the National Allocation of Cadaveric Renal Allografts
Background. National sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these kidneys despite increasing cold storage times. However, there may be limits to outcome improvement of matched kidneys based on age and cold st...
Saved in:
Published in | The Journal of surgical research Vol. 91; no. 1; pp. 83 - 88 |
---|---|
Main Authors | , , , , , , , , |
Format | Journal Article Conference Proceeding |
Language | English |
Published |
New York, NY
Elsevier Inc
01.06.2000
Elsevier |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Background. National sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these kidneys despite increasing cold storage times. However, there may be limits to outcome improvement of matched kidneys based on age and cold storage time.
Materials and methods. To determine if national sharing of kidneys based on matching improves outcome regardless of donor age and cold storage time, we evaluated the United Network for Organ Sharing (UNOS) Scientific Registry for all recipients of cadaveric kidney transplants between January 1, 1990 and July 31, 1998. We divided the recipients into four groups based on donor age and cold storage time. Group 1 comprised young donors (donor age <55 years) with average (<24 h) cold storage time; group 2, young donors with long (≥24 h) cold storage time; group 3, older donors (donor age ≥55 years) with average cold storage time; and group 4, older donors with long cold storage time.
Results. A total of 64,046 recipients were evaluated: 35,061 (55%) in group 1, 21,264 (33%) in group 2, 4308 (7%) in group 3, and 3414 (5%) in group 4. Early graft performance progressively decreased from group 1 to group 4. Delayed graft function (DGF: dialysis requirement in the first 7 days posttransplant) was 18, 29, 33, and 42% (P < 0.0001); serum creatinine at 3 years (in mg/dl) was 1.70 ± 0.8, 1.73 ± 0.9, 2.31 ± 1.0, and 2.42 ± 1.1 (P < 0.0001); 1-year graft survival was 87, 84, 79, and 77% (P < 0.0001); and 3-year graft survival was 77, 74, 63, and 62% (P < 0.0001, for groups 1 and 2 vs groups 3 and 4, respectively). The trends in DGF persisted through the groups in 0 antigen mismatched kidneys.
Conclusions. Early function is adversely affected by prolonged cold storage, despite matching, in recipients of younger and older donor kidneys. Long-term function does not appear to be affected by prolonged cold storage. Recipients of kidneys from donors ≥55 years of age have significantly worse short- and long-term outcome and may not benefit from national sharing. |
---|---|
AbstractList | BACKGROUNDNational sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these kidneys despite increasing cold storage times. However, there may be limits to outcome improvement of matched kidneys based on age and cold storage time.MATERIALS AND METHODSTo determine if national sharing of kidneys based on matching improves outcome regardless of donor age and cold storage time, we evaluated the United Network for Organ Sharing (UNOS) Scientific Registry for all recipients of cadaveric kidney transplants between January 1, 1990 and July 31, 1998. We divided the recipients into four groups based on donor age and cold storage time. Group 1 comprised young donors (donor age <55 years) with average (<24 h) cold storage time; group 2, young donors with long (>/=24 h) cold storage time; group 3, older donors (donor age >/=55 years) with average cold storage time; and group 4, older donors with long cold storage time.RESULTSA total of 64,046 recipients were evaluated: 35,061 (55%) in group 1, 21,264 (33%) in group 2, 4308 (7%) in group 3, and 3414 (5%) in group 4. Early graft performance progressively decreased from group 1 to group 4. Delayed graft function (DGF: dialysis requirement in the first 7 days posttransplant) was 18, 29, 33, and 42% (P < 0.0001); serum creatinine at 3 years (in mg/dl) was 1.70 +/- 0.8, 1.73 +/- 0.9, 2. 31 +/- 1.0, and 2.42 +/- 1.1 (P < 0.0001); 1-year graft survival was 87, 84, 79, and 77% (P < 0.0001); and 3-year graft survival was 77, 74, 63, and 62% (P < 0.0001, for groups 1 and 2 vs groups 3 and 4, respectively). The trends in DGF persisted through the groups in 0 antigen mismatched kidneys.CONCLUSIONSEarly function is adversely affected by prolonged cold storage, despite matching, in recipients of younger and older donor kidneys. Long-term function does not appear to be affected by prolonged cold storage. Recipients of kidneys from donors >/=55 years of age have significantly worse short- and long-term outcome and may not benefit from national sharing. Background. National sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these kidneys despite increasing cold storage times. However, there may be limits to outcome improvement of matched kidneys based on age and cold storage time. Materials and methods. To determine if national sharing of kidneys based on matching improves outcome regardless of donor age and cold storage time, we evaluated the United Network for Organ Sharing (UNOS) Scientific Registry for all recipients of cadaveric kidney transplants between January 1, 1990 and July 31, 1998. We divided the recipients into four groups based on donor age and cold storage time. Group 1 comprised young donors (donor age <55 years) with average (<24 h) cold storage time; group 2, young donors with long (≥24 h) cold storage time; group 3, older donors (donor age ≥55 years) with average cold storage time; and group 4, older donors with long cold storage time. Results. A total of 64,046 recipients were evaluated: 35,061 (55%) in group 1, 21,264 (33%) in group 2, 4308 (7%) in group 3, and 3414 (5%) in group 4. Early graft performance progressively decreased from group 1 to group 4. Delayed graft function (DGF: dialysis requirement in the first 7 days posttransplant) was 18, 29, 33, and 42% (P < 0.0001); serum creatinine at 3 years (in mg/dl) was 1.70 ± 0.8, 1.73 ± 0.9, 2.31 ± 1.0, and 2.42 ± 1.1 (P < 0.0001); 1-year graft survival was 87, 84, 79, and 77% (P < 0.0001); and 3-year graft survival was 77, 74, 63, and 62% (P < 0.0001, for groups 1 and 2 vs groups 3 and 4, respectively). The trends in DGF persisted through the groups in 0 antigen mismatched kidneys. Conclusions. Early function is adversely affected by prolonged cold storage, despite matching, in recipients of younger and older donor kidneys. Long-term function does not appear to be affected by prolonged cold storage. Recipients of kidneys from donors ≥55 years of age have significantly worse short- and long-term outcome and may not benefit from national sharing. National sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these kidneys despite increasing cold storage times. However, there may be limits to outcome improvement of matched kidneys based on age and cold storage time. To determine if national sharing of kidneys based on matching improves outcome regardless of donor age and cold storage time, we evaluated the United Network for Organ Sharing (UNOS) Scientific Registry for all recipients of cadaveric kidney transplants between January 1, 1990 and July 31, 1998. We divided the recipients into four groups based on donor age and cold storage time. Group 1 comprised young donors (donor age <55 years) with average (<24 h) cold storage time; group 2, young donors with long (>/=24 h) cold storage time; group 3, older donors (donor age >/=55 years) with average cold storage time; and group 4, older donors with long cold storage time. A total of 64,046 recipients were evaluated: 35,061 (55%) in group 1, 21,264 (33%) in group 2, 4308 (7%) in group 3, and 3414 (5%) in group 4. Early graft performance progressively decreased from group 1 to group 4. Delayed graft function (DGF: dialysis requirement in the first 7 days posttransplant) was 18, 29, 33, and 42% (P < 0.0001); serum creatinine at 3 years (in mg/dl) was 1.70 +/- 0.8, 1.73 +/- 0.9, 2. 31 +/- 1.0, and 2.42 +/- 1.1 (P < 0.0001); 1-year graft survival was 87, 84, 79, and 77% (P < 0.0001); and 3-year graft survival was 77, 74, 63, and 62% (P < 0.0001, for groups 1 and 2 vs groups 3 and 4, respectively). The trends in DGF persisted through the groups in 0 antigen mismatched kidneys. Early function is adversely affected by prolonged cold storage, despite matching, in recipients of younger and older donor kidneys. Long-term function does not appear to be affected by prolonged cold storage. Recipients of kidneys from donors >/=55 years of age have significantly worse short- and long-term outcome and may not benefit from national sharing. |
Author | Hiose, Ryutaro Stock, Peter G Melzer, Juliet S Freise, Chris E Dafoe, Donald C Lee, Crystine M Carter, Jonathan T Randall, Henry B Alfrey, Edward J |
Author_xml | – sequence: 1 givenname: Crystine M surname: Lee fullname: Lee, Crystine M organization: Department of Surgery, School of Medicine, University of California, San Francisco, San Francisco, California, 94143 – sequence: 2 givenname: Jonathan T surname: Carter fullname: Carter, Jonathan T organization: Department of Surgery, School of Medicine, Stanford University, 251 Campus Drive, MSOBx338, Stanford, California, 94305 – sequence: 3 givenname: Henry B surname: Randall fullname: Randall, Henry B organization: Department of Surgery, School of Medicine, University of California, San Francisco, San Francisco, California, 94143 – sequence: 4 givenname: Ryutaro surname: Hiose fullname: Hiose, Ryutaro organization: Department of Surgery, School of Medicine, University of California, San Francisco, San Francisco, California, 94143 – sequence: 5 givenname: Peter G surname: Stock fullname: Stock, Peter G organization: Department of Surgery, School of Medicine, University of California, San Francisco, San Francisco, California, 94143 – sequence: 6 givenname: Juliet S surname: Melzer fullname: Melzer, Juliet S organization: Department of Surgery, School of Medicine, University of California, San Francisco, San Francisco, California, 94143 – sequence: 7 givenname: Donald C surname: Dafoe fullname: Dafoe, Donald C organization: Department of Surgery, School of Medicine, Stanford University, 251 Campus Drive, MSOBx338, Stanford, California, 94305 – sequence: 8 givenname: Chris E surname: Freise fullname: Freise, Chris E organization: Department of Surgery, School of Medicine, University of California, San Francisco, San Francisco, California, 94143 – sequence: 9 givenname: Edward J surname: Alfrey fullname: Alfrey, Edward J organization: Department of Surgery, School of Medicine, Stanford University, 251 Campus Drive, MSOBx338, Stanford, California, 94305 |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1397630$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/10816355$$D View this record in MEDLINE/PubMed |
BookMark | eNp1kUFvEzEQRi1URNPClSPyAXHbMLbXu95jFBWoVAFC4Ww59jh15V0Xe1OJf4-XBMGF08iaN59mnq_IxZQmJOQ1gzUD6N4_lIxrDgBrOXD2jKwYDLJRXS8uyAqA86ZV0F6Sq1IeKsWHXrwglwwU64SUKxJ390hvvEc70-Tp5oDUTI5-zSmm6YCOblN09LbYexyDobswYqFponMd-2zmkCYT6SbGZH8_loytceYJc7D0G_7pHrLxc3lJnnsTC74612vy_cPNbvupufvy8Xa7uWus6Ia5EWZwSnHY-1YZkKbz0AEXoret3IOsjXpH2xvJ2t7voVMdF9LLwVrDpUMprsm7U-5jTj-OWGY9hmIxRjNhOhbdM8ZB9qqC6xNocyrVpNePOYwm_9QM9OJXL3714lcvfuvAm3PycT-i-wc_Ca3A2zNgijXRZzPZUP5yYug7ARVTJwyrhqeAWRcbcLLoQq5foV0K_1vhF58glok |
CODEN | JSGRA2 |
CitedBy_id | crossref_primary_10_1111_j_1399_0012_2010_01239_x crossref_primary_10_2215_CJN_13711119 crossref_primary_10_5812_numonthly_12182 crossref_primary_10_1111_j_1399_0012_2007_00789_x crossref_primary_10_1097_TP_0b013e3181a6b4ff crossref_primary_10_1016_j_transproceed_2010_04_038 crossref_primary_10_1097_TXD_0000000000001354 crossref_primary_10_1258_ce_2011_011029 crossref_primary_10_2478_v10035_011_0029_1 crossref_primary_10_1016_S0041_1345_03_00798_X crossref_primary_10_1111_j_1600_6143_2005_01095_x crossref_primary_10_1016_S0302_2838_03_00380_4 crossref_primary_10_1097_01_TP_0000159143_45022_F6 crossref_primary_10_1067_msy_2002_124629 crossref_primary_10_1111_ctr_12555 crossref_primary_10_1016_S0041_1345_00_02333_2 crossref_primary_10_1111_j_1447_0578_2007_00200_x crossref_primary_10_1016_j_transproceed_2011_07_015 crossref_primary_10_1007_s11255_012_0235_8 crossref_primary_10_1034_j_1399_0012_2002_02044_x crossref_primary_10_1034_j_1600_6143_3_s4_11_x crossref_primary_10_1111_j_1600_6143_2004_00622_x crossref_primary_10_1159_000072055 crossref_primary_10_1081_JDI_120004092 crossref_primary_10_1016_j_transproceed_2022_08_042 crossref_primary_10_1111_j_1399_0012_2006_00508_x crossref_primary_10_1111_j_1600_6143_2007_02014_x crossref_primary_10_1016_j_transproceed_2009_11_021 crossref_primary_10_1097_TP_0000000000001363 crossref_primary_10_1111_j_1432_2277_2002_tb00104_x crossref_primary_10_1097_01_tp_0000269610_13590_52 crossref_primary_10_1586_1744666X_4_3_391 crossref_primary_10_1071_RD06007 crossref_primary_10_1034_j_1399_0012_2003_00061_x crossref_primary_10_1097_01_TP_0000161225_89368_81 crossref_primary_10_1016_S0041_1345_03_00021_6 crossref_primary_10_1111_j_1399_3046_2008_01054_x crossref_primary_10_1097_TP_0b013e3181f2c962 crossref_primary_10_1016_j_transproceed_2003_10_034 |
Cites_doi | 10.1097/00007890-199812270-00022 10.1097/00007890-199403270-00018 10.1097/00007890-199801270-00011 10.1056/NEJM199209173271202 10.1016/S0022-5347(01)67046-0 10.1097/00007890-199706150-00015 10.1097/00007890-199706150-00013 10.1097/00007890-199001000-00020 10.1016/S0002-9610(96)00233-4 |
ContentType | Journal Article Conference Proceeding |
Copyright | 2000 Academic Press 2000 INIST-CNRS Copyright 2000 Academic Press. |
Copyright_xml | – notice: 2000 Academic Press – notice: 2000 INIST-CNRS – notice: Copyright 2000 Academic Press. |
DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1006/jsre.2000.5921 |
DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE - Academic MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
EISSN | 1095-8673 |
EndPage | 88 |
ExternalDocumentID | 10_1006_jsre_2000_5921 10816355 1397630 S0022480400959213 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GeographicLocations | United States |
GeographicLocations_xml | – name: United States |
GrantInformation_xml | – fundername: Association for Aacademic Surgery |
GroupedDBID | --- --K --M .55 .GJ .~1 0R~ 1B1 1RT 1~. 1~5 29L 3O- 457 4CK 4G. 53G 5GY 5RE 5VS 7-5 71M 8P~ 9JM AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXUO ABBQC ABJNI ABLVK ABMAC ABYKQ ACDAQ ACGFS ACRLP ADBBV ADEZE ADFGL ADMUD AEKER AENEX AFCTW AFFNX AFKWA AFTJW AFXIZ AGHFR AGUBO AGYEJ AHHHB AHPSJ AIEXJ AIKHN AITUG AJBFU AJOXV AJRQY ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CAG COF CS3 DM4 DU5 EBS EFBJH EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-Q HVGLF HZ~ IHE J1W KOM LCYCR LG5 M29 M41 MO0 N9A O-L O9- OAUVE OZT P-9 P2P PC. Q38 R2- RIG ROL RPZ SAE SCC SDF SDG SDP SEL SES SPCBC SSH SSZ T5K UHS X7M XPP ZA5 ZGI ZMT ZU3 ~G- .1- .FO 08R 1P~ 4.4 AAUGY ABFNM ABMZM ABPIF ABPTK ABXDB AEBSH AEVXI AFRHN AJUYK G-2 GBLVA HEK HMK HMO IQODW J5H OK- OW- P-8 SEW WUQ Z5R ZXP AKRWK CGR CUY CVF ECM EIF NPM AAXKI AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c369t-3a9d8820bf48a05a6f0602337c45b0520b02947a5147fb0686235f59cca25de53 |
IEDL.DBID | AIKHN |
ISSN | 0022-4804 |
IngestDate | Fri Aug 16 01:38:52 EDT 2024 Thu Sep 12 20:11:40 EDT 2024 Thu May 23 23:03:50 EDT 2024 Sun Oct 22 16:06:23 EDT 2023 Fri Feb 23 02:31:21 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 1 |
Keywords | Kidney disease Human Graft(material) Urinary system disease Homograft Cardiovascular disease Transplantation Survival Kidney Vascular disease Treatment Ischemia Cryopreservation Graft Complication Age Cadaver |
Language | English |
License | CC BY 4.0 Copyright 2000 Academic Press. |
LinkModel | DirectLink |
MeetingName | Presented at the Annual Meeting of the Association of Academic Surgery, Philadelphia, Pennsylvania, November 18-22, 1999 |
MergedId | FETCHMERGED-LOGICAL-c369t-3a9d8820bf48a05a6f0602337c45b0520b02947a5147fb0686235f59cca25de53 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 10816355 |
PQID | 71120578 |
PQPubID | 23479 |
PageCount | 6 |
ParticipantIDs | proquest_miscellaneous_71120578 crossref_primary_10_1006_jsre_2000_5921 pubmed_primary_10816355 pascalfrancis_primary_1397630 elsevier_sciencedirect_doi_10_1006_jsre_2000_5921 |
PublicationCentury | 2000 |
PublicationDate | 2000-06-01 |
PublicationDateYYYYMMDD | 2000-06-01 |
PublicationDate_xml | – month: 06 year: 2000 text: 2000-06-01 day: 01 |
PublicationDecade | 2000 |
PublicationPlace | New York, NY |
PublicationPlace_xml | – name: New York, NY – name: United States |
PublicationTitle | The Journal of surgical research |
PublicationTitleAlternate | J Surg Res |
PublicationYear | 2000 |
Publisher | Elsevier Inc Elsevier |
Publisher_xml | – name: Elsevier Inc – name: Elsevier |
References | Terasaki, Gjertson, Cecka, Takemoto, Cho (RF16) 1997; 11 Busson, Benoit, N'Doye, Hors (RF7) 1995; 154 Blumke, Keller, Elbe, Nausner, Kirste (RF6) 1992; 24 Rao, Kasiske, Odlund, Ney, Anderson (RF8) 1990; 49 Lloveras, Arias, Puig (RF13) 1995; 27 Takemoto, Terasaki, Cecka, Yong, Gjertson (RF18) 1992; 327 Shoskes, Cecka (RF20) 1998; 66 Nghiem, Cottington, Hsia (RF14) 1993; 25 Cosio, Pelletier, Falkenhain, Henry, Elkhammas, Davies, Bumgardner, Ferguson (RF19) 1997; 63 Kuo, Johnson, Schweitzer, Alfrey, Waskerwitz, Bartlett (RF5) 1996; 172 Koka, Cecka (RF17) 1990; 4 UNOS 1998 Annual Report of the U.S. Scientific Registry of Transplant Recipients and the Organ Procurement and Transplantation Network, from the UNOS website at . Cecka, Terasaki (RF3) 1995; 27 Segoloni, Messina, Triolo, Cogno, Amoroso, Vercellone (RF11) 1991; 23 Kumar, Stephan, Chui, Chvala, Olshan, Krevolin, Abouna (RF12) 1993; 25 Sautner, Gotzinger, Wamser, Gnant, Steininger, Muhlbacher (RF9) 1991; 23 Alexander, Bennett, Breen (RF2) 1994; 57 Ablaza, Morris, Badosa, Anderson, Raja, Mital (RF15) 1993; 25 Hata, Cecka, Takemoto, Ozawa, Cho, Terasaki (RF1) 1998; 65 Lloveras (RF4) 1991; 23 Koning, Ploeg, van Bockel, Groenewegen, Van Der Woulde, Persijn, Hermans (RF10) 1997; 63 10.1006/jsre.2000.5921_RF21 Hata (10.1006/jsre.2000.5921_RF1) 1998; 65 Koka (10.1006/jsre.2000.5921_RF17) 1990; 4 Ablaza (10.1006/jsre.2000.5921_RF15) 1993; 25 Takemoto (10.1006/jsre.2000.5921_RF18) 1992; 327 Kumar (10.1006/jsre.2000.5921_RF12) 1993; 25 Cosio (10.1006/jsre.2000.5921_RF19) 1997; 63 Sautner (10.1006/jsre.2000.5921_RF9) 1991; 23 Segoloni (10.1006/jsre.2000.5921_RF11) 1991; 23 Lloveras (10.1006/jsre.2000.5921_RF13) 1995; 27 Lloveras (10.1006/jsre.2000.5921_RF4) 1991; 23 Kuo (10.1006/jsre.2000.5921_RF5) 1996; 172 Nghiem (10.1006/jsre.2000.5921_RF14) 1993; 25 Alexander (10.1006/jsre.2000.5921_RF2) 1994; 57 Koning (10.1006/jsre.2000.5921_RF10) 1997; 63 Cecka (10.1006/jsre.2000.5921_RF3) 1995; 27 Terasaki (10.1006/jsre.2000.5921_RF16) 1997; 11 Shoskes (10.1006/jsre.2000.5921_RF20) 1998; 66 Busson (10.1006/jsre.2000.5921_RF7) 1995; 154 Rao (10.1006/jsre.2000.5921_RF8) 1990; 49 Blumke (10.1006/jsre.2000.5921_RF6) 1992; 24 |
References_xml | – volume: 65 start-page: 208 year: 1998 ident: RF1 article-title: Effects of changes in the criteria for national shared kidney transplants for HLA-matched patients publication-title: Transplantation contributor: fullname: Terasaki – volume: 27 start-page: 981 year: 1995 ident: RF13 article-title: Five-year follow-up of 250 recipients of cadaveric kidney allografts from donors older than 55 years of age publication-title: Transplant. Proc. contributor: fullname: Puig – volume: 172 start-page: 551 year: 1996 ident: RF5 article-title: Utilization of the older donor for renal transplantation publication-title: Am. J. Surg. contributor: fullname: Bartlett – volume: 154 start-page: 356 year: 1995 ident: RF7 article-title: Analysis of cadaver donor criteria on the kidney transplant survival rate in 5,129 transplantations publication-title: J. Urol. contributor: fullname: Hors – volume: 25 start-page: 2183 year: 1993 ident: RF12 article-title: Effect of donor age on graft function and graft survival in cadaver renal transplantation publication-title: Transplant. Proc. contributor: fullname: Abouna – volume: 57 start-page: 871 year: 1994 ident: RF2 article-title: Effect of donor age on outcome of kidney transplantation publication-title: Transplantation contributor: fullname: Breen – volume: 49 start-page: 91 year: 1990 ident: RF8 article-title: Influence of cadaver donor age on posttransplant renal function and graft outcome publication-title: Transplantation contributor: fullname: Anderson – volume: 23 start-page: 2592 year: 1991 ident: RF4 article-title: The elderly donor publication-title: Transplant. Proc. contributor: fullname: Lloveras – volume: 23 start-page: 2598 year: 1991 ident: RF9 article-title: Impact of donor age on graft function in 1180 consecutive kidney recipients publication-title: Transplant. Proc. contributor: fullname: Muhlbacher – volume: 63 start-page: 1620 year: 1997 ident: RF10 article-title: Risk factors for delayed graft function in cadaveric kidney transplantation publication-title: Transplantation contributor: fullname: Hermans – volume: 25 start-page: 1554 year: 1993 ident: RF15 article-title: Kidneys from cadaveric donors over 60 years of age publication-title: Transplant. Proc. contributor: fullname: Mital – volume: 11 start-page: 366 year: 1997 ident: RF16 article-title: Significance of donor age effect on kidney transplants publication-title: Clin. Transplant. contributor: fullname: Cho – volume: 66 start-page: 1697 year: 1998 ident: RF20 article-title: Deleterious effects of delayed graft functioning cadaveric renal transplant recipients independent of acute rejection publication-title: Clin. Transpl. contributor: fullname: Cecka – volume: 327 start-page: 834 year: 1992 ident: RF18 article-title: Survival of nationally shared kidney transplants from cadaveric donors publication-title: N. Engl. J. Med. contributor: fullname: Gjertson – volume: 25 start-page: 567 year: 1993 ident: RF14 article-title: Transplantation of the extreme age donor kidneys publication-title: Transplant. Proc. contributor: fullname: Hsia – volume: 63 start-page: 1611 year: 1997 ident: RF19 article-title: Impact of acute rejection and early allograft function on renal allograft survival publication-title: Transplantation contributor: fullname: Ferguson – volume: 23 start-page: 2620 year: 1991 ident: RF11 article-title: Impact of donor age in kidney transplantation publication-title: Transplant. Proc. contributor: fullname: Vercellone – volume: 4 start-page: 437 year: 1990 ident: RF17 article-title: Sex and age effects in renal transplantation publication-title: Clin. Transpl. contributor: fullname: Cecka – volume: 24 start-page: 2728 year: 1992 ident: RF6 article-title: Donor age is a risk factor in cadaver kidney transplantation publication-title: Transplant. Proc. contributor: fullname: Kirste – volume: 27 start-page: 801 year: 1995 ident: RF3 article-title: Optimal use for older donor kidneys: Older recipients publication-title: Transplant. Proc. contributor: fullname: Terasaki – volume: 66 start-page: 1697 year: 1998 ident: 10.1006/jsre.2000.5921_RF20 article-title: Deleterious effects of delayed graft functioning cadaveric renal transplant recipients independent of acute rejection publication-title: Clin. Transpl. doi: 10.1097/00007890-199812270-00022 contributor: fullname: Shoskes – volume: 57 start-page: 871 year: 1994 ident: 10.1006/jsre.2000.5921_RF2 article-title: Effect of donor age on outcome of kidney transplantation publication-title: Transplantation doi: 10.1097/00007890-199403270-00018 contributor: fullname: Alexander – volume: 23 start-page: 2598 year: 1991 ident: 10.1006/jsre.2000.5921_RF9 article-title: Impact of donor age on graft function in 1180 consecutive kidney recipients publication-title: Transplant. Proc. contributor: fullname: Sautner – volume: 25 start-page: 2183 year: 1993 ident: 10.1006/jsre.2000.5921_RF12 article-title: Effect of donor age on graft function and graft survival in cadaver renal transplantation publication-title: Transplant. Proc. contributor: fullname: Kumar – volume: 24 start-page: 2728 year: 1992 ident: 10.1006/jsre.2000.5921_RF6 article-title: Donor age is a risk factor in cadaver kidney transplantation publication-title: Transplant. Proc. contributor: fullname: Blumke – volume: 27 start-page: 801 year: 1995 ident: 10.1006/jsre.2000.5921_RF3 article-title: Optimal use for older donor kidneys: Older recipients publication-title: Transplant. Proc. contributor: fullname: Cecka – volume: 4 start-page: 437 year: 1990 ident: 10.1006/jsre.2000.5921_RF17 article-title: Sex and age effects in renal transplantation publication-title: Clin. Transpl. contributor: fullname: Koka – volume: 65 start-page: 208 year: 1998 ident: 10.1006/jsre.2000.5921_RF1 article-title: Effects of changes in the criteria for national shared kidney transplants for HLA-matched patients publication-title: Transplantation doi: 10.1097/00007890-199801270-00011 contributor: fullname: Hata – volume: 11 start-page: 366 year: 1997 ident: 10.1006/jsre.2000.5921_RF16 article-title: Significance of donor age effect on kidney transplants publication-title: Clin. Transplant. contributor: fullname: Terasaki – volume: 327 start-page: 834 year: 1992 ident: 10.1006/jsre.2000.5921_RF18 article-title: Survival of nationally shared kidney transplants from cadaveric donors publication-title: N. Engl. J. Med. doi: 10.1056/NEJM199209173271202 contributor: fullname: Takemoto – volume: 23 start-page: 2620 year: 1991 ident: 10.1006/jsre.2000.5921_RF11 article-title: Impact of donor age in kidney transplantation publication-title: Transplant. Proc. contributor: fullname: Segoloni – volume: 25 start-page: 567 year: 1993 ident: 10.1006/jsre.2000.5921_RF14 article-title: Transplantation of the extreme age donor kidneys publication-title: Transplant. Proc. contributor: fullname: Nghiem – volume: 23 start-page: 2592 year: 1991 ident: 10.1006/jsre.2000.5921_RF4 article-title: The elderly donor publication-title: Transplant. Proc. contributor: fullname: Lloveras – volume: 154 start-page: 356 year: 1995 ident: 10.1006/jsre.2000.5921_RF7 article-title: Analysis of cadaver donor criteria on the kidney transplant survival rate in 5,129 transplantations publication-title: J. Urol. doi: 10.1016/S0022-5347(01)67046-0 contributor: fullname: Busson – volume: 63 start-page: 1620 year: 1997 ident: 10.1006/jsre.2000.5921_RF10 article-title: Risk factors for delayed graft function in cadaveric kidney transplantation publication-title: Transplantation doi: 10.1097/00007890-199706150-00015 contributor: fullname: Koning – volume: 27 start-page: 981 year: 1995 ident: 10.1006/jsre.2000.5921_RF13 article-title: Five-year follow-up of 250 recipients of cadaveric kidney allografts from donors older than 55 years of age publication-title: Transplant. Proc. contributor: fullname: Lloveras – volume: 63 start-page: 1611 year: 1997 ident: 10.1006/jsre.2000.5921_RF19 article-title: Impact of acute rejection and early allograft function on renal allograft survival publication-title: Transplantation doi: 10.1097/00007890-199706150-00013 contributor: fullname: Cosio – volume: 49 start-page: 91 year: 1990 ident: 10.1006/jsre.2000.5921_RF8 article-title: Influence of cadaver donor age on posttransplant renal function and graft outcome publication-title: Transplantation doi: 10.1097/00007890-199001000-00020 contributor: fullname: Rao – volume: 25 start-page: 1554 year: 1993 ident: 10.1006/jsre.2000.5921_RF15 article-title: Kidneys from cadaveric donors over 60 years of age publication-title: Transplant. Proc. contributor: fullname: Ablaza – volume: 172 start-page: 551 year: 1996 ident: 10.1006/jsre.2000.5921_RF5 article-title: Utilization of the older donor for renal transplantation publication-title: Am. J. Surg. doi: 10.1016/S0002-9610(96)00233-4 contributor: fullname: Kuo – ident: 10.1006/jsre.2000.5921_RF21 |
SSID | ssj0002973 |
Score | 1.833364 |
Snippet | Background. National sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these... National sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these kidneys... BACKGROUNDNational sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these... |
SourceID | proquest crossref pubmed pascalfrancis elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 83 |
SubjectTerms | Adolescent Adult Age Factors Aged Biological and medical sciences Cadaver Cryopreservation Graft Survival Humans Ischemia Kidney Transplantation Medical sciences Middle Aged Registries Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Time Factors Tissue and Organ Procurement - organization & administration Tissue and Organ Procurement - standards Transplantation, Homologous Treatment Outcome United States |
Title | The Effect of Age and Prolonged Cold Ischemia Times on the National Allocation of Cadaveric Renal Allografts |
URI | https://dx.doi.org/10.1006/jsre.2000.5921 https://www.ncbi.nlm.nih.gov/pubmed/10816355 https://search.proquest.com/docview/71120578 |
Volume | 91 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8NAEB60vQgiiq-q1T0IntKmSTbpHktRqoKIKPQWJtndUqlJaatHf7szefg49OIxCbtZZnbn-3Z3HgCXqYepl7qpY1AVp1WKlpTVjpdoaVBGqbaFg-xDOHoJ7sZyvAHDOhaG3Sor21_a9MJaV2-6lTS78-mUY3wJfvo8CZVUHleubRIcBUEDmoPb-9HDt0Hm8kx10nBuUOdudMPuK-FQEa3S4S7WYdP2HJckMVuWuljPRQtMutmFnYpMikE53j3YMNk-zEjzokxKLHIrBhMjMNPicUFmLpsYLYb5TItb2tWatymKIgZE5JkgJiiqLNnU5YxBjh-4jyFq_OCbHfFk6q-TBdrV8gBebq6fhyOnqqngpH6oVo6PShOpdhMb9NGVGFo3JNj2ozSQCfvEJCSuIELiUZFNivgRX1qpSNGe1Eb6h9DI8swcg_BoN2QtKh8jPyCipLSbhCaxoYq8AD3TgqtamvG8TJ0Rl0mSw5jlzhUw3Zjl3oJeLez4j_Jjsutr27T_aOXnF8ywfLcFF7WWYloxfA2Cmcnfl3FEFJNYar8FR6Xyfo2u32MCdvKP8ZzCVhmlzwc0Z9BYLd5Nm_jKKjmHzc5n77yalV-Sh-iH |
link.rule.ids | 310,311,315,786,790,795,796,4521,23958,23959,24144,25170,27957,27958,45620,45714 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La-MwEB5KemhhWVq27Wa3Dx0WenLj2JYdHUNoSLZpWJYEehNjSwopWTsk6f7-nfFj2x5y6dE2ksU30swnaR4AP7IAsyDzM8-iKk-rFC0pZ7wgNdKiTDLjSgfZaTyaRz-f5NMBDJpYGHarrHV_pdNLbV2_6dRodtbLJcf4kvnp8SRUUgVcufYwkkk3asFhf_wwmv5XyFyeqUkazg2a3I1-3HkmO1RGq9xxF_ts06c1bgkxV5W62M9FS5s0PIHPNZkU_Wq8p3Bg8y-wIsmLKimxKJzoL6zA3IhfG1Jz-cIaMShWRoxpV2v_LFGUMSCiyAUxQVFnyaYuV2zk-IH7GKDBv3yzI37b5utig263PYP58H42GHl1TQUvC2O180JUhki1n7qoh77E2Pkxme0wySKZsk9MSnBFCRKPSlxaxo-E0klFgg6ksTI8h1Ze5PYriIB2Q86hCjEJIyJKyvhpbFMXqySIMLBtuG3Q1OsqdYaukiTHmnHnCpi-Ztzb0G3A1u-Er0mv721z9U4qr79ghhX6bbhppKRpxfA1COa2eNnqhCgmsdReGy4q4b0ZXa_LBOzbB8ZzA0ej2eNET8bTh-9wXEXs82HNJbR2mxd7Rdxll17Xc_MfLyTqeQ |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=proceeding&rft.title=The+Journal+of+surgical+research&rft.atitle=The+effect+of+age+and+prolonged+cold+ischemia+times+on+the+national+allocation+of+cadaveric+renal+allografts&rft.au=LEE%2C+C.+M&rft.au=CARTER%2C+J.+T&rft.au=RANDALL%2C+H.+B&rft.au=HIOSE%2C+R&rft.date=2000-06-01&rft.pub=Elsevier&rft.issn=0022-4804&rft.eissn=1095-8673&rft.volume=91&rft.issue=1&rft.spage=83&rft.epage=88&rft_id=info:doi/10.1006%2Fjsre.2000.5921&rft.externalDBID=n%2Fa&rft.externalDocID=1397630 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-4804&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-4804&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-4804&client=summon |