Familial combined hyperlipoproteinemia. Evidence for a role of growth hormone deficiency in effecting its manifestation

• Published in: The Journal of clinical investigation Vol. 65; no. 4; pp. 829 - 835
• Main Author: Merimee, T J
• Format: Journal Article
• Language: English
• Published: United States 01.04.1980
• Subjects: Adult; Aged; Basal Metabolism; Blood Glucose - metabolism; Dwarfism, Pituitary - complications; Dwarfism, Pituitary - genetics; Dwarfism, Pituitary - metabolism; Female; Glucose Tolerance Test; Growth Hormone - deficiency; Growth Hormone - therapeutic use; Humans; Hyperlipidemia, Familial Combined - etiology; Insulin - pharmacology; Male; Middle Aged; Pedigree

Hyperlipidemia associated with an isolated deficiency of growth hormone was investigated in 10 subjects with hypercholesterolemia consistently present over a 10-yr period. 8 of these 10 had serum triglyceride concentrations greater than 185 mg/dl. 13 growth hormone-deficient patients with normal ser...