Advances in proteomics sample preparation and enrichment for phosphorylation and glycosylation analysis

• Published in: Proteomics (Weinheim) Vol. 22; no. 23-24; pp. e2200070 - n/a
• Main Authors: Xie, Zehu, Feng, Quanshou, Zhang, Shun, Yan, Yinghua, Deng, Chunhui, Ding, Chuan‐Fan
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.12.2022
• Subjects: Enrichment; Glycosylation; Impurities; Ionization; Mass spectrometry; Mass spectroscopy; Phosphoproteomes; Phosphorylation; post‐translational modifications; Protein Processing, Post-Translational; Proteome - metabolism; Proteomes; Proteomics; Proteomics - methods; Sample preparation; sample preparation and enrichment; proteomics; sample preparation and enrichment; post-translational modifications

As the common and significant chemical modifications, post‐translational modifications (PTMs) play a key role in the functional proteome. Affected by the signal interference, low concentration, and insufficient ionization efficiency of impurities, the direct detection of PTMs by mass spectrometry (M...