Safety of the standardized quality tree sublingual immunotherapy tablet: Pooled safety analysis of clinical trials

• Published in: Allergy (Copenhagen) Vol. 76; no. 12; pp. 3733 - 3742
• Main Authors: Biedermann, Tilo, Couroux, Peter, Greve, Tina Maria, Mäkelä, Mika
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.12.2021
• Subjects: Adolescent; Adolescents; Adult; Aged; Allergens; Allergic rhinitis; allergy treatment; Asthma; Child; Clinical trials; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Conjunctivitis; Double-Blind Method; Food allergies; food allergy; Humans; Hypersensitivity; Immunotherapy; Irritation; Medical personnel; Middle Aged; Oral administration; Placebos; Pollen; Pruritus; Randomized Controlled Trials as Topic; rhinitis; Rhinitis, Allergic - therapy; Safety; Sublingual Immunotherapy - adverse effects; Tablets; Treatment Outcome; vaccines; Young Adult; allergy treatment; rhinitis; pollen; vaccines; food allergy
• ISSN: 0105-4538; 1398-9995; 1398-9995
• DOI: 10.1111/all.14882

Background The standardized quality (SQ) tree sublingual immunotherapy (SLIT)‐tablet has recently been approved for treatment of tree pollen allergy. Healthcare workers should be provided with detailed safety data for clinical use. Objective To assess the tolerability and safety of the SQ tree SLIT‐...