Disorganization and cognitive impairment in schizophrenia: New insights from electrophysiological findings

• Published in: International journal of psychophysiology Vol. 145; pp. 99 - 108
• Main Authors: Vignapiano, Annarita, Koenig, Thomas, Mucci, Armida, Giordano, Giulia M., Amodio, Antonella, Altamura, Mario, Bellomo, Antonello, Brugnoli, Roberto, Corrivetti, Giulio, Di Lorenzo, Giorgio, Girardi, Paolo, Monteleone, Palmiero, Niolu, Cinzia, Galderisi, Silvana, Maj, Mario
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.11.2019
• Subjects: Adult; Alpha rhythm; Brain - physiopathology; Brain Waves - physiology; Cognition - physiology; Cognitive Dysfunction - physiopathology; Difficulty in abstract thinking; Disorganization dimension; Electroencephalography; Female; Humans; Male; Middle Aged; Neurocognitive domains; Neuropsychological Tests; Problem Solving - physiology; Schizophrenia - physiopathology; Schizophrenic Psychology; Spectral power; Topographic analysis; Young Adult; Alpha rhythm; Topographic analysis; Difficulty in abstract thinking; Neurocognitive domains; Spectral power; Disorganization dimension

In subjects with schizophrenia (SCZ), the disorganization dimension is a strong predictor of real-life functioning. “Conceptual disorganization” (P2), “Difficulty in abstract thinking” (N5) and “Poor attention” (G11) are core features of the disorganization factor, evaluated using the Positive and N...