Immunoglobulin G4-related hepatic inflammatory pseudotumor invading the abdominal wall
A 50-year-old woman presented with epigastralgia. Computed tomography (CT) of the abdomen revealed a 6-cm well-enhanced mass extending from the left lobe of the liver to the abdominal wall, suggestive of cholangiocarcinoma. Liver and skin mass biopsies did not provide evidence of hepatic malignancy...
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| Published in | Clinical journal of gastroenterology Vol. 10; no. 1; pp. 57 - 62 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Tokyo
Springer Japan
01.02.2017
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| Abstract | A 50-year-old woman presented with epigastralgia. Computed tomography (CT) of the abdomen revealed a 6-cm well-enhanced mass extending from the left lobe of the liver to the abdominal wall, suggestive of cholangiocarcinoma. Liver and skin mass biopsies did not provide evidence of hepatic malignancy but were rich in plasma cells and sclerotic lesions. Subsequent detection of elevated serum immunoglobulin G4 (IgG4) led to a diagnosis IgG4-related inflammatory pseudotumor (IPT) of the liver. Treatment with systemic corticosteroids resulted in rapid clinical improvement. This case is the first report of an IgG4-related hepatic IPT invading the abdominal wall. |
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| AbstractList | A 50-year-old woman presented with epigastralgia. Computed tomography (CT) of the abdomen revealed a 6-cm well-enhanced mass extending from the left lobe of the liver to the abdominal wall, suggestive of cholangiocarcinoma. Liver and skin mass biopsies did not provide evidence of hepatic malignancy but were rich in plasma cells and sclerotic lesions. Subsequent detection of elevated serum immunoglobulin G4 (IgG4) led to a diagnosis IgG4-related inflammatory pseudotumor (IPT) of the liver. Treatment with systemic corticosteroids resulted in rapid clinical improvement. This case is the first report of an IgG4-related hepatic IPT invading the abdominal wall. |
| Author | Okano, Akihiro Ohana, Masaya Miyajima, Shinji |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27909975$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.2214/ajr.161.4.8372760 10.1038/modpathol.3800836 10.2214/ajr.167.2.8686633 10.1097/01.pas.0000136449.37936.6c 10.1148/radiology.211.2.r99ma36373 10.1002/1097-0142(19900401)65:7<1583::AID-CNCR2820650722>3.0.CO;2-L 10.1016/S0720-048X(97)00128-9 10.1097/00000478-199303000-00003 10.2214/ajr.163.5.7976880 10.1186/1752-1947-5-196 10.5009/gnl.2014.8.1.58 10.3109/s10165-011-0571-z 10.1007/s12328-015-0605-8 10.1136/bcr-2015-211893 |
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| References_xml | – volume: 161 start-page: 791 year: 1993 end-page: 794 ident: CR13 article-title: Abdominal actinomycosis: CT findings in 10 patients publication-title: Am J Roentgenol doi: 10.2214/ajr.161.4.8372760 contributor: fullname: Kim – volume: 20 start-page: 884 year: 2007 end-page: 894 ident: CR3 article-title: Pathological classification of hepatic inflammatory pseudotumor with respect to IgG4-related disease publication-title: Mod Pathol doi: 10.1038/modpathol.3800836 contributor: fullname: Sato – volume: 15 start-page: 151 year: 2009 end-page: 156 ident: CR6 article-title: Imaging of inflammatory pseudotumor of the liver publication-title: Liver Cancer contributor: fullname: Fukusato – volume: 167 start-page: 485 year: 1996 end-page: 487 ident: CR7 article-title: Inflammatory pseudotumor of the liver: CT and sonographic imagings publication-title: Am J Roentgenol doi: 10.2214/ajr.167.2.8686633 contributor: fullname: Lim – volume: 28 start-page: 1193 year: 2004 end-page: 1203 ident: CR15 article-title: IgG4-related sclerosing cholangitis with and without hepatic inflammatory pseudotumor, and sclerosing pancreatitis-associated sclerosing cholangitis: do they belong to a spectrum of sclerosing pancreatitis? publication-title: Am J Surg Pathol doi: 10.1097/01.pas.0000136449.37936.6c contributor: fullname: Sasaki – volume: 211 start-page: 373 year: 1999 end-page: 379 ident: CR10 article-title: Inflammatory pseudotumor of the liver in patients with recurrent pyogenic cholangitis: CT histopathologic correlation publication-title: Radiology doi: 10.1148/radiology.211.2.r99ma36373 contributor: fullname: Lee – volume: 65 start-page: 1583 year: 1990 end-page: 1590 ident: CR4 article-title: Inflammatory pseudotumor of the liver. 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| SubjectTerms | Abdominal Surgery Abdominal Wall - pathology Bile Duct Neoplasms - diagnosis Biopsy Case Report Cholangiocarcinoma - diagnosis Colorectal Surgery Diagnosis, Differential Female Gastroenterology Granuloma, Plasma Cell - diagnostic imaging Granuloma, Plasma Cell - immunology Granuloma, Plasma Cell - pathology Hepatology Humans Immunoglobulin G - blood Liver - pathology Liver Diseases - diagnostic imaging Liver Diseases - immunology Liver Diseases - pathology Magnetic Resonance Imaging Medicine Medicine & Public Health Middle Aged Skin - pathology Surgical Oncology Tomography, X-Ray Computed Ultrasonography |
| Title | Immunoglobulin G4-related hepatic inflammatory pseudotumor invading the abdominal wall |
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