Upper airway effective compliance during wakefulness and sleep in obese adolescents studied via two-dimensional dynamic MRI and semiautomated image segmentation

• Published in: Journal of applied physiology (1985) Vol. 131; no. 2; pp. 532 - 543
• Main Authors: Choy, Kok Ren, Sin, Sanghun, Tong, Yubing, Udupa, Jayaram K., Luchtenburg, Dirk M., Wagshul, Mark E., Arens, Raanan, Wootton, David M.
• Format: Journal Article
• Language: English
• Published: Bethesda American Physiological Society 01.08.2021
• Subjects: Aerodynamics; Air flow; Apnea; Biomarkers; Biomechanics; Children; Cluster analysis; Clustering; Compliance; Computational fluid dynamics; Computer applications; Cross-sections; Diagnostic systems; Estimation; Flow velocity; Fluid dynamics; Hydrodynamics; Image filters; Image processing; Image segmentation; Innovative Methodology; Magnetic resonance imaging; Mathematical analysis; Mechanical properties; Medical imaging; Obesity; Pressure; Respiratory tract; Singular value decomposition; Sleep; Sleep and wakefulness; Sleep disorders; Teenagers; Vector quantization; Wakefulness

This study investigated the dynamics of the upper airway at retropalatal and retroglossal sites during wakefulness and sleep by evaluating the effective compliance (EC) of each site and its correlation with apnea-hypopnea index (AHI) using novel semiautomated image processing. AHI correlated signifi...