Evaluating and Improving Syndrome Differentiation Thinking Ability in Large Language Models: Method Development Study

• Published in: JMIR medical informatics Vol. 13; p. e75103
• Main Authors: Chen, Chunliang, Wang, Xinyu, Guan, Ming, Yue, Wenjing, Wu, Yuanbin, Zhou, Ya, Wang, Xiaoling
• Format: Journal Article
• Language: English
• Published: Canada JMIR Publications 20.06.2025
• Subjects: Diagnosis, Differential; Humans; Knowledge; Language; Large Language Models; Medical records; Medicine, Chinese Traditional - methods; Pathogenesis; Quantitative analysis; Syndrome; Thinking; Traditional Chinese medicine; TCM LLMs; RAG; traditional Chinese medicine; large language model; instruction tuning; syndrome differentiation thinking

A large language model (LLM) provides new opportunities to advance the intelligent development of traditional Chinese medicine (TCM). Syndrome differentiation thinking is an essential part of TCM and equipping LLMs with this capability represents a crucial step toward more effective clinical applica...