Structural Features of the Interfaces in Enzyme-Inhibitor Complexes

• Published in: Journal of biomolecular structure & dynamics Vol. 28; no. 1; pp. 85 - 96
• Main Authors: Nekrasov, Alexei N., Zinchenko, Alexei A.
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis Group 01.08.2010
• Subjects: Algorithms; Amino Acid Sequence; Animals; Binding Sites; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - metabolism; Enzyme-inhibitor complex; Enzymes - chemistry; Enzymes - metabolism; Informational structure of proteins; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Interaction Mapping - methods; Protein-protein interaction; Sequence Analysis, Protein - methods

Specific protein-protein interaction is essential for the function of life systems. A variety of computational methods are being extensively used now-a-days to investigate this interaction and to identify structural features of binding sites. In this paper, the informational structure analysis metho...