Age-related characteristics of the efficacy of different glucocorticosteroids in the therapy of acute lymphoblastic leukemia

• Published in: Terapevtic̆eskii arhiv Vol. 87; no. 7; pp. 41 - 50
• Main Authors: Karachunsky, A I, Rumyantseva, Yu V, Lagoiko, S N, Bührer, C, Tallen, G, Aleinikova, O V, Bydanov, O I, Korepanova, N V, Baidun, L V, Nasedkina, T V, Stackelberg, A Von, Novichkova, G A, Maschan, A A, Litvinov, D V, Ponomareva, N I, Kondratchik, K L, Mansurova, E G, Fechina, L G, Streneva, O V, Yudina, N B, Sharapova, G R, Shamardina, A V, Gerbek, I E, Shapochnik, A P, Rumyantsev, A G, Henze, G
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) "Consilium Medicum" Publishing house 01.01.2015
• Subjects: acute lymphoblastic leukemia; Adolescent; Age Distribution; Age Factors; Child; Child, Preschool; children; dexamethasone; Dexamethasone - therapeutic use; Female; Glucocorticoids - therapeutic use; glucocorticosteroids; Humans; Incidence; induction; Infant; Male; Methylprednisolone - therapeutic use; Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma - epidemiology; prednisolone; Prospective Studies; Republic of Belarus - epidemiology; Russia - epidemiology; Survival Rate - trends; therapy; Treatment Outcome; Young Adult; Republic of Belarus; Russia

To determine predictors for decision-making on a differential approach to choosing glucocorticosteroids (GCS) for children and adolescents with acute lymphoblastic leukemia (ALL). The analysis covered 1064 primary patients aged to 1 to 18 years with ALL who had been registered at the clinics of Russ...