Phenotypic characterisation of Clostridium difficile PCR ribotype 251, an emerging multi-locus sequence type clade 2 strain in Australia

• Published in: Anaerobe Vol. 60; p. 102066
• Main Authors: Hong, Stacey, Knight, Daniel R., Chang, Barbara, Carman, Robert J., Riley, Thomas V.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2019
• Subjects: Anti-Bacterial Agents - pharmacology; Antimicrobial resistance; Australia - epidemiology; Bacterial Toxins - genetics; Clostridium difficile; Clostridium difficile - classification; Clostridium difficile - drug effects; Clostridium difficile - genetics; Clostridium Infections - epidemiology; Clostridium Infections - microbiology; Enterotoxins - genetics; Enzyme-Linked Immunosorbent Assay; Genotype; Germination; Humans; Microbial Sensitivity Tests; Multilocus Sequence Typing; Phenotype; Phylogeny; Polymerase Chain Reaction; Public Health Surveillance; Ribotyping; Spores, Bacterial - drug effects; Sporulation; Virulence factors; Australia; Antimicrobial resistance; Virulence factors; Sporulation; Germination; Clostridium difficile

The global emergence of epidemic Clostridium difficile PCR ribotype (RT) 027 prompted enhanced surveillance of emerging strains. Recently, there have been reports of severe C. difficile infection in Australia caused by an unusual strain of C. difficile not seen previously. Identified as PCR RT251, t...