Hyaluronic acid-quercetin pendant drug conjugate for wound healing applications

• Published in: International journal of biological macromolecules Vol. 240; p. 124336
• Main Authors: Rao, Kummara Madhusudana, Kim, Eunbi, Kim, Hyeon Jin, Uthappa, Uluvangada Thammaiah, Han, Sung Soo
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.06.2023
• Subjects: Antioxidants - chemistry; Hyaluronic acid; Hyaluronic Acid - chemistry; Pendant conjugate; Quercetin; Quercetin - chemistry; Quercetin - pharmacology; Water; Wound Healing; Wound healing; Pendant conjugate; Hyaluronic acid; Quercetin

In this study, a simple approach was used for the synthesis of a water-soluble hyaluronic acid-quercetin (HA-Q) pendant drug conjugate to evaluate its potential wound-healing properties. The HA-Q conjugation was confirmed by Fourier-transform infrared spectroscopy (FTIR), ultraviolet–visible spectro...