A New Transcutaneous Method for Breast Cancer Detection with Dogs

We developed a new transcutaneous method for breast cancer detection with dogs: 2 dogs were trained to sniff skin secretion samples on compresses that had been worn overnight by women on their breast, and to recognize a breast cancer sample among 4 samples. During the test, the dogs recognized 90.3%...

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Published inOncology Vol. 96; no. 2; p. 110
Main Authors Thuleau, Aurélie, Gilbert, Caroline, Bauër, Pierre, Alran, Séverine, Fourchotte, Virginie, Guillot, Eugénie, Vincent-Salomon, Anne, Kerihuel, Jean-Charles, Dugay, José, Semetey, Vincent, Kriegel, Irène, Fromantin, Isabelle
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.2019
Subjects
Adult
Aged
Aged, 80 and over
Animals
Breast Neoplasms - diagnosis
Breast Neoplasms - metabolism
Dogs - physiology
Female
Humans
Middle Aged
Skin - metabolism
Smell
Volatile Organic Compounds - analysis
Volatile Organic Compounds - metabolism
Breast cancer
Detection
Dog
Sniffer dog
Online AccessGet more information

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Abstract We developed a new transcutaneous method for breast cancer detection with dogs: 2 dogs were trained to sniff skin secretion samples on compresses that had been worn overnight by women on their breast, and to recognize a breast cancer sample among 4 samples. During the test, the dogs recognized 90.3% of skin secretion breast cancer samples. This proof-of-concept study opens new avenues for the development of a reliable cancer diagnostic tool integrating olfactory abilities of dogs.
AbstractList We developed a new transcutaneous method for breast cancer detection with dogs: 2 dogs were trained to sniff skin secretion samples on compresses that had been worn overnight by women on their breast, and to recognize a breast cancer sample among 4 samples. During the test, the dogs recognized 90.3% of skin secretion breast cancer samples. This proof-of-concept study opens new avenues for the development of a reliable cancer diagnostic tool integrating olfactory abilities of dogs.
Author Thuleau, Aurélie
Gilbert, Caroline
Alran, Séverine
Guillot, Eugénie
Dugay, José
Semetey, Vincent
Fourchotte, Virginie
Kriegel, Irène
Fromantin, Isabelle
Bauër, Pierre
Vincent-Salomon, Anne
Kerihuel, Jean-Charles
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  givenname: Aurélie
  surname: Thuleau
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  organization: Wound Care Unit, Anesthesia, Intensive Care and Pain Management Department, Institut Curie, Paris, France
– sequence: 2
  givenname: Caroline
  surname: Gilbert
  fullname: Gilbert, Caroline
  organization: Université Paris-Est, Ecole Nationale Vétérinaire d'Alfort, UMR 7179, Laboratoire Mecadev, CNRS/MNHN, Maisons-Alfort, France
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  givenname: Pierre
  surname: Bauër
  fullname: Bauër, Pierre
  organization: Wound Care Unit, Anesthesia, Intensive Care and Pain Management Department, Institut Curie, Paris, France
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  givenname: Séverine
  surname: Alran
  fullname: Alran, Séverine
  organization: Surgery Department, Institut Curie, Paris, France
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  givenname: Virginie
  surname: Fourchotte
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  organization: Surgery Department, Institut Curie, Paris, France
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  givenname: Eugénie
  surname: Guillot
  fullname: Guillot, Eugénie
  organization: Surgery Department, Institut Curie, Paris, France
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  givenname: Anne
  surname: Vincent-Salomon
  fullname: Vincent-Salomon, Anne
  organization: Pathology and Biology of Tumors Department, Institut Curie, Paris, France
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  givenname: Jean-Charles
  surname: Kerihuel
  fullname: Kerihuel, Jean-Charles
  organization: Société Verticale, Paris, France
– sequence: 9
  givenname: José
  surname: Dugay
  fullname: Dugay, José
  organization: Analytical, Bioanalytical and Miniaturization Sciences, UMR PECSA 7195 ESPCI, Paris, France
– sequence: 10
  givenname: Vincent
  surname: Semetey
  fullname: Semetey, Vincent
  organization: Chimie ParisTech, PSL Research University, CNRS, Institut de Recherche de Chimie Paris, Paris, France
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  givenname: Irène
  surname: Kriegel
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  organization: Wound Care Unit, Anesthesia, Intensive Care and Pain Management Department, Institut Curie, Paris, France
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  givenname: Isabelle
  surname: Fromantin
  fullname: Fromantin, Isabelle
  email: Franceisabelle.fromantin@curie.fr
  organization: Wound Care Unit, Anesthesia, Intensive Care and Pain Management Department, Institut Curie, Paris, Franceisabelle.fromantin@curie.fr
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Keywords Breast cancer
Detection
Dog
Sniffer dog
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Snippet We developed a new transcutaneous method for breast cancer detection with dogs: 2 dogs were trained to sniff skin secretion samples on compresses that had been...
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SubjectTerms Adult
Aged
Aged, 80 and over
Animals
Breast Neoplasms - diagnosis
Breast Neoplasms - metabolism
Dogs - physiology
Female
Humans
Middle Aged
Skin - metabolism
Smell
Volatile Organic Compounds - analysis
Volatile Organic Compounds - metabolism
Title A New Transcutaneous Method for Breast Cancer Detection with Dogs
URI https://www.ncbi.nlm.nih.gov/pubmed/30278460
Volume 96
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