Gold nanoparticles modified reduced graphene oxide nanosheets based dual-quencher for highly sensitive detection of carcinoembryonic antigen
In the current scenario, the dominance of cancer is becoming a disastrous threat to mankind. Therefore, an advanced analytical approach is desired as the need of the hour for early diagnosis to curb the menace of cancer. In this context, the present work reports the development of nano surface energ...
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| Published in | International journal of biological macromolecules Vol. 242; no. Pt 4; p. 125157 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
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Elsevier B.V
01.07.2023
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| Abstract | In the current scenario, the dominance of cancer is becoming a disastrous threat to mankind. Therefore, an advanced analytical approach is desired as the need of the hour for early diagnosis to curb the menace of cancer. In this context, the present work reports the development of nano surface energy transfer (NSET) based fluorescent immunosensor for carcinoembryonic antigen (CEA) detection utilizing protein functionalized graphene quantum dots (anti-CEA/amine-GQDs) and a nanocomposite of nanostructured gold and reduced graphene oxide (AuNPs@rGO) as energy donor-acceptor pair, respectively. The obtained AuNPs@rGO nanocomposite has been characterized by different advanced analytical techniques. The functionality of the biosensor depends on quenching the fluorescence of anti-CEA/amine-GQDs donor species by AuNPs@rGO acceptor species, followed by the gradual recovery of GQDs' fluorescence after CEA addition. The efficient energy transfer kinetics have been envisaged by utilizing the AuNPs@rGO nanocomposite as a dual-quencher nanoprobe that revealed improved energy transfer and quenching efficiency (∼62 %, 88 %) compared to AuNPs (∼43 %, 81 %) as a single quencher. Further, the developed biosensing platform successfully detected CEA biomarker with notable biosensing parameters, including a wider linear detection range (0.001–500 ng mL−1), fast response time (24 min), and a significantly low detection limit (0.35 pg mL−1).
•Synthesis of AuNPs@rGO nanocomposite via one-pot reduction method.•anti-CEA/amine-GQDs and AuNPs@rGO are used as NSET donor-acceptor pair.•AuNPs@rGO as dual-quencher reveal better quenching efficiency than AuNPs.•The NSET-based fluorescent immunosensor is fabricated for CEA detection.•Remarkable biosensing performance is obtained in standard and spiked serum samples. |
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| AbstractList | In the current scenario, the dominance of cancer is becoming a disastrous threat to mankind. Therefore, an advanced analytical approach is desired as the need of the hour for early diagnosis to curb the menace of cancer. In this context, the present work reports the development of nano surface energy transfer (NSET) based fluorescent immunosensor for carcinoembryonic antigen (CEA) detection utilizing protein functionalized graphene quantum dots (anti-CEA/amine-GQDs) and a nanocomposite of nanostructured gold and reduced graphene oxide (AuNPs@rGO) as energy donor-acceptor pair, respectively. The obtained AuNPs@rGO nanocomposite has been characterized by different advanced analytical techniques. The functionality of the biosensor depends on quenching the fluorescence of anti-CEA/amine-GQDs donor species by AuNPs@rGO acceptor species, followed by the gradual recovery of GQDs' fluorescence after CEA addition. The efficient energy transfer kinetics have been envisaged by utilizing the AuNPs@rGO nanocomposite as a dual-quencher nanoprobe that revealed improved energy transfer and quenching efficiency (∼62 %, 88 %) compared to AuNPs (∼43 %, 81 %) as a single quencher. Further, the developed biosensing platform successfully detected CEA biomarker with notable biosensing parameters, including a wider linear detection range (0.001-500 ng mL
), fast response time (24 min), and a significantly low detection limit (0.35 pg mL
). In the current scenario, the dominance of cancer is becoming a disastrous threat to mankind. Therefore, an advanced analytical approach is desired as the need of the hour for early diagnosis to curb the menace of cancer. In this context, the present work reports the development of nano surface energy transfer (NSET) based fluorescent immunosensor for carcinoembryonic antigen (CEA) detection utilizing protein functionalized graphene quantum dots (anti-CEA/amine-GQDs) and a nanocomposite of nanostructured gold and reduced graphene oxide (AuNPs@rGO) as energy donor-acceptor pair, respectively. The obtained AuNPs@rGO nanocomposite has been characterized by different advanced analytical techniques. The functionality of the biosensor depends on quenching the fluorescence of anti-CEA/amine-GQDs donor species by AuNPs@rGO acceptor species, followed by the gradual recovery of GQDs' fluorescence after CEA addition. The efficient energy transfer kinetics have been envisaged by utilizing the AuNPs@rGO nanocomposite as a dual-quencher nanoprobe that revealed improved energy transfer and quenching efficiency (∼62 %, 88 %) compared to AuNPs (∼43 %, 81 %) as a single quencher. Further, the developed biosensing platform successfully detected CEA biomarker with notable biosensing parameters, including a wider linear detection range (0.001–500 ng mL−1), fast response time (24 min), and a significantly low detection limit (0.35 pg mL−1). •Synthesis of AuNPs@rGO nanocomposite via one-pot reduction method.•anti-CEA/amine-GQDs and AuNPs@rGO are used as NSET donor-acceptor pair.•AuNPs@rGO as dual-quencher reveal better quenching efficiency than AuNPs.•The NSET-based fluorescent immunosensor is fabricated for CEA detection.•Remarkable biosensing performance is obtained in standard and spiked serum samples. |
| ArticleNumber | 125157 |
| Author | Pradhan, Rangadhar Packirisamy, Gopinath Kalkal, Ashish |
| Author_xml | – sequence: 1 givenname: Ashish surname: Kalkal fullname: Kalkal, Ashish email: ashishkalkal222@gmail.com organization: Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand 247667, India – sequence: 2 givenname: Rangadhar surname: Pradhan fullname: Pradhan, Rangadhar email: rangadhar@gmail.com organization: iHub Divyasmapark, Technology Innovation hub, Indian Institute of Technology Roorkee, Uttarakhand 247667, India – sequence: 3 givenname: Gopinath surname: Packirisamy fullname: Packirisamy, Gopinath email: gopi@bt.iitr.ac.in organization: Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand 247667, India |
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| Cites_doi | 10.1039/C5AN02094H 10.1038/srep23406 10.1007/s12274-011-0116-y 10.1039/C7RA05491B 10.1021/acs.jpcc.8b06539 10.1088/1742-6596/704/1/012011 10.1016/j.snb.2018.11.141 10.1007/s00216-018-1501-0 10.1007/s10895-017-2095-1 10.7150/thno.33858 10.1002/cncr.33587 10.1016/j.bios.2012.11.039 10.1016/j.bios.2019.111815 10.1016/j.ijsu.2015.11.065 10.1039/c2cc35645g 10.1016/j.breast.2020.05.005 10.1007/s10544-021-00545-4 10.1038/srep07515 10.1016/j.nanoso.2022.100886 10.1021/ac403635f 10.1021/ac5003905 10.1016/j.snb.2014.09.084 10.1016/j.bios.2017.11.004 10.1016/j.jallcom.2018.04.293 10.1158/1055-9965.EPI-19-0221 10.1016/j.jpba.2022.115120 10.7150/ntno.81485 10.1021/acsabm.0c00427 10.1016/j.bios.2016.11.002 10.1103/PhysRevB.26.5409 10.1016/j.sintl.2021.100102 10.1039/C5TB02169C 10.1016/j.snb.2017.07.129 10.1039/D1MA00251A 10.1039/D2CC03996F 10.1016/j.bios.2017.09.003 10.1007/s11748-008-0397-6 10.1021/ac500351d 10.1088/1361-6528/ab3566 10.1016/j.trac.2019.115748 10.1016/j.jviromet.2020.113926 10.1039/C5TB00885A 10.1021/acsanm.1c02967 10.1016/j.bios.2021.113620 10.1016/j.bios.2015.11.084 10.1016/j.jpba.2022.115102 10.1038/srep30849 10.1038/s41598-021-98513-8 10.1016/j.tranon.2020.100907 10.1021/acsbiomaterials.1c01087 10.1016/j.bios.2015.05.040 10.1016/B978-0-12-818154-6.00008-1 10.1109/TIM.2023.3275998 10.1021/nl903178n 10.1039/C4RA14833A 10.3322/caac.21660 10.1039/c2an35099h 10.1016/j.electacta.2015.07.086 10.1016/j.snb.2014.09.028 |
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| Keywords | Nano surface energy transfer (NSET) Nanocomposite Carcinoembryonic antigen (CEA) Cancer diagnosis Dual-quencher |
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| References | Mahato, Nagpal, Shah, Srivastava, Maurya, Roy, Jaiswal, Singh, Chandra (bb0175) 2019; 9 Chen, Hildebrandt (bb0170) 2020; 123 Kumar, Kumar, Srivastava, Yadav, Lee, Sharma, Doval, Malhotra (bb0305) 2015; 73 K. Z. Yap, W. Y. Lim, A. Kalkal, P. Gopinath, N. Ramakrishnan, Electrophoretic Deposited Mg Ion Functionalised Graphene Oxide based Ultra-Highly Sensitive Humidity Sensor," in, IEEE Transactions on Instrumentation and Measurement, doi:10.1109/TIM.2023.3275998. Bohunicky, Mousa (bb0020) 2010; 4 Sung, Ferlay, Siegel, Laversanne, Soerjomataram, Jemal, Bray (bb0010) 2021; 71 Sørensen, Karlsson, Pommergaard, Burcharth, Rosenberg (bb0040) 2016; 25 Hirotsu, Mochizuki, Omata (bb0205) 2020; 284 Wu, Li, Liu (bb0270) 2015; 206 Kalkal, Kadian, Pradhan, Manik, Packirisamy (bb0145) 2021; 2 Kumar, Sharma, Maji, Malhotra (bb0210) 2016; 78 Hu, He, Zhang, Wu, Li, Zhao, Qiao, Lu, Liu, Li (bb0300) 2014; 86 Tade, Patil (bb0050) 2022; 8 Quan, Zuo, Li, Liu, Li, Zhong, Zhang, Qi, Yang (bb0310) 2015; 176 Tian, Liu, Li, Wei, Cao (bb0280) 2016; 6 Cui, Ji, Sun, Wang, Wang, Zhang, Ding, Lu, Xu, Sun (bb0110) 2019; 411 Zhang, Chen, Xing, Guo, Xu, Wang, Gruber, Zhang, Tang (bb0235) 2011; 4 Kalkal, Kadian, Kumar, Manik, Sen, Kumar, Packirisamy (bb0200) 2022; 195 Pradhan, Raisa, Kumar, Kalkal, Kumar, Packirisamy, Manhas (bb0225) 2021; 23 Schabath, Cote (bb0045) 2019; 28 Wang, Chu, Shen, Deng, Yan, Ge, Yu, Song (bb0285) 2015; 206 Huang, Aryal, Tam-Chang, Publicover, Hunter (bb0195) 2016; 141 Yang, Xu, Huang, Jiang, Gong, Liu, Kuang, Yang (bb0060) 2021; 11 Zhang, Sun, Ji, Pi, Xiao, Zhang, Sun (bb0115) 2019; 282 Xie, Meng, Li, Wang, Qian, Chan, Yu, Fan, Pan, Xie, Wu, Yan, Liu, Tang, Yao, Wang, Leung (bb0015) 2021; 14 Kalkal, Packirisamy (bb0180) 2022 Gentleman, Lawson, Ellis, Davis, Turner-Dore, Ryder, Frosz, Ciaccia, Reisner, Cresswell, Euser (bb0250) 2022; 58 Xu, Dong, Zhou, Yin, Cui, Xu, Chen, Song (bb0325) 2016; 6 Song, Xu, Xing, Li, Zhou, Liu, Song (bb0215) 2014; 4 S. Kumar, A. Kalkal, 3 - electrochemical detection: cyclic voltammetry/differential pulse voltammetry/impedance spectroscopy, in: K.R. Khondakar, A.K. Kaushik (Eds.), Nanotechnology in Cancer Management, Elsevier2021, pp. 43–71. https://doi.org/10.1016/B978-0-12-818154-6.00008-1. Malode, Shanbhag, Kumari, Dkhar, Chandra, Shetti (bb0155) 2023; 222 Kalkal, Pradhan, Kadian, Manik, Packirisamy (bb0160) 2020; 3 Ji, He, Shen, Hu, Li, Jiang, Zhang, Li, Zhu (bb0290) 2014; 86 Wang, Wang, Wu, Ma, Zhang, Fan, Pang, Du, Wei (bb0320) 2018; 255 Malhotra, Kumar, Pandey (bb0025) 2016; 704 Kumar, Ashish, Augustine, Yadav, Yadav, Chauhan, Dewan, Malhotra (bb0220) 2018; 102 Hing, Mok, Tan, Sudhakar, Seah, Lee, Tan (bb0035) 2020; 52 Kumar, Basak, Kalkal, Packirisamy (bb0105) 2022; 31 Siontorou, Nikoleli, Nikolelis, Karapetis, Tzamtzis, Bratakou (bb0080) 2017 Mayilo, Kloster, Wunderlich, Lutich, Klar, Nichtl, Kürzinger, Stefani, Feldmann (bb0260) 2009; 9 Fu, Gu, Zhao, Zhou, Zhang (bb0135) 2017; 27 Shi, Tian, Lyu, Yang (bb0140) 2015; 3 Mahato, Purohit, Kumar, Chandra (bb0240) 2020; 148 Yuan, Yu, Zhang, Xu, Cheng, Tu, Ding (bb0190) 2017; 92 Romero, Picchio (bb0095) 2020 Chandra (bb0100) 2023; 7 Dutta (bb0090) 2020 Mahato, Kumar, Maurya, Chandra (bb0070) 2018; 100 Chen, Zeng, Si, Chen, Chi, Kim, Chen (bb0295) 2014; 86 Tomita, Shimizu, Hara, Ayabe, Onitsuka (bb0055) 2009; 57 Bray, Laversanne, Weiderpass, Soerjomataram (bb0005) 2021; 127 Padmavathi, Bordoloi, Banik, Kunnumakkara (bb0075) 2017 Sandil, Srivastava, Malhotra, Sharma, Puri (bb0230) 2018; 763 Lin, Jiang, Cheng, Li, Shuai, Zhang, Liu, Li, Huang (bb0120) 2021; 4 Persson, Lang (bb0125) 1982; 26 Kumar, Willander, Sharma, Malhotra (bb0275) 2015; 3 Ali, Singh, Srivastava, Admane, Agrawal, Sumana, John, Panda, Dong, Malhotra (bb0245) 2017; 7 Kalkal, Allawadhi, Pradhan, Khurana, Bharani, Packirisamy (bb0165) 2021; 2 Li, Zhou, Guo, Wu (bb0185) 2013; 43 Luo, Wen, Lin, Zhang, Gu, Wang (bb0315) 2015; 5 Huang, Shi, Li, Luo (bb0255) 2012; 137 Lin, Zhang, Yang, Qiu, Chen (bb0265) 2012; 48 Kadian, Manik, Kalkal, Singh, Chauhan (bb0150) 2019; 30 Chen, Midelet, Bhuckory, Hildebrandt, Werts (bb0130) 2018; 122 Gomes, Almeida, Barreira, Calheiros, Pinto, Abrantes, Costa, Polonia, Campos, Osório, Sousa, Pinto-de-Sousa, Kolarich, Reis (bb0030) 2019; 9 Dkhar, Kumari, Malode, Shetti, Chandra (bb0085) 2023; 223 Gentleman (10.1016/j.ijbiomac.2023.125157_bb0250) 2022; 58 Romero (10.1016/j.ijbiomac.2023.125157_bb0095) 2020 Cui (10.1016/j.ijbiomac.2023.125157_bb0110) 2019; 411 Zhang (10.1016/j.ijbiomac.2023.125157_bb0115) 2019; 282 Bohunicky (10.1016/j.ijbiomac.2023.125157_bb0020) 2010; 4 Huang (10.1016/j.ijbiomac.2023.125157_bb0195) 2016; 141 Huang (10.1016/j.ijbiomac.2023.125157_bb0255) 2012; 137 Kalkal (10.1016/j.ijbiomac.2023.125157_bb0145) 2021; 2 Li (10.1016/j.ijbiomac.2023.125157_bb0185) 2013; 43 Malode (10.1016/j.ijbiomac.2023.125157_bb0155) 2023; 222 Lin (10.1016/j.ijbiomac.2023.125157_bb0265) 2012; 48 Luo (10.1016/j.ijbiomac.2023.125157_bb0315) 2015; 5 Hu (10.1016/j.ijbiomac.2023.125157_bb0300) 2014; 86 Mahato (10.1016/j.ijbiomac.2023.125157_bb0175) 2019; 9 Sandil (10.1016/j.ijbiomac.2023.125157_bb0230) 2018; 763 Fu (10.1016/j.ijbiomac.2023.125157_bb0135) 2017; 27 Ji (10.1016/j.ijbiomac.2023.125157_bb0290) 2014; 86 Hing (10.1016/j.ijbiomac.2023.125157_bb0035) 2020; 52 Wang (10.1016/j.ijbiomac.2023.125157_bb0320) 2018; 255 Kalkal (10.1016/j.ijbiomac.2023.125157_bb0200) 2022; 195 Siontorou (10.1016/j.ijbiomac.2023.125157_bb0080) 2017 Kumar (10.1016/j.ijbiomac.2023.125157_bb0210) 2016; 78 Schabath (10.1016/j.ijbiomac.2023.125157_bb0045) 2019; 28 Tian (10.1016/j.ijbiomac.2023.125157_bb0280) 2016; 6 Chen (10.1016/j.ijbiomac.2023.125157_bb0170) 2020; 123 Kumar (10.1016/j.ijbiomac.2023.125157_bb0275) 2015; 3 Wu (10.1016/j.ijbiomac.2023.125157_bb0270) 2015; 206 Sung (10.1016/j.ijbiomac.2023.125157_bb0010) 2021; 71 Xu (10.1016/j.ijbiomac.2023.125157_bb0325) 2016; 6 Tomita (10.1016/j.ijbiomac.2023.125157_bb0055) 2009; 57 Chen (10.1016/j.ijbiomac.2023.125157_bb0130) 2018; 122 Kalkal (10.1016/j.ijbiomac.2023.125157_bb0160) 2020; 3 Malhotra (10.1016/j.ijbiomac.2023.125157_bb0025) 2016; 704 Chen (10.1016/j.ijbiomac.2023.125157_bb0295) 2014; 86 Dutta (10.1016/j.ijbiomac.2023.125157_bb0090) 2020 Shi (10.1016/j.ijbiomac.2023.125157_bb0140) 2015; 3 Bray (10.1016/j.ijbiomac.2023.125157_bb0005) 2021; 127 10.1016/j.ijbiomac.2023.125157_bb0065 Quan (10.1016/j.ijbiomac.2023.125157_bb0310) 2015; 176 Kadian (10.1016/j.ijbiomac.2023.125157_bb0150) 2019; 30 Mahato (10.1016/j.ijbiomac.2023.125157_bb0070) 2018; 100 Kumar (10.1016/j.ijbiomac.2023.125157_bb0305) 2015; 73 Lin (10.1016/j.ijbiomac.2023.125157_bb0120) 2021; 4 10.1016/j.ijbiomac.2023.125157_bb5000 Kumar (10.1016/j.ijbiomac.2023.125157_bb0220) 2018; 102 Kalkal (10.1016/j.ijbiomac.2023.125157_bb0165) 2021; 2 Zhang (10.1016/j.ijbiomac.2023.125157_bb0235) 2011; 4 Hirotsu (10.1016/j.ijbiomac.2023.125157_bb0205) 2020; 284 Chandra (10.1016/j.ijbiomac.2023.125157_bb0100) 2023; 7 Mahato (10.1016/j.ijbiomac.2023.125157_bb0240) 2020; 148 Padmavathi (10.1016/j.ijbiomac.2023.125157_bb0075) 2017 Yang (10.1016/j.ijbiomac.2023.125157_bb0060) 2021; 11 Tade (10.1016/j.ijbiomac.2023.125157_bb0050) 2022; 8 Ali (10.1016/j.ijbiomac.2023.125157_bb0245) 2017; 7 Yuan (10.1016/j.ijbiomac.2023.125157_bb0190) 2017; 92 Wang (10.1016/j.ijbiomac.2023.125157_bb0285) 2015; 206 Persson (10.1016/j.ijbiomac.2023.125157_bb0125) 1982; 26 Kalkal (10.1016/j.ijbiomac.2023.125157_bb0180) 2022 Kumar (10.1016/j.ijbiomac.2023.125157_bb0105) 2022; 31 Dkhar (10.1016/j.ijbiomac.2023.125157_bb0085) 2023; 223 Pradhan (10.1016/j.ijbiomac.2023.125157_bb0225) 2021; 23 Xie (10.1016/j.ijbiomac.2023.125157_bb0015) 2021; 14 Sørensen (10.1016/j.ijbiomac.2023.125157_bb0040) 2016; 25 Gomes (10.1016/j.ijbiomac.2023.125157_bb0030) 2019; 9 Song (10.1016/j.ijbiomac.2023.125157_bb0215) 2014; 4 Mayilo (10.1016/j.ijbiomac.2023.125157_bb0260) 2009; 9 |
| References_xml | – start-page: 115 year: 2017 end-page: 132 ident: bb0080 article-title: Point-of-care and implantable biosensors in Cancer research and diagnosis publication-title: Next Generation Point-of-Care Biomedical Sensors Technologies for Cancer Diagnosis contributor: fullname: Bratakou – volume: 58 start-page: 10548 year: 2022 end-page: 10551 ident: bb0250 article-title: Stern–Volmer analysis of photocatalyst fluorescence quenching within hollow-core photonic crystal fibre microreactors publication-title: Chem. Commun. contributor: fullname: Euser – volume: 206 start-page: 531 year: 2015 end-page: 537 ident: bb0270 article-title: An aptasensor for carcinoembryonic antigen based on upconversion fluorescence resonance energy transfer publication-title: Sensors Actuators B Chem. contributor: fullname: Liu – volume: 86 start-page: 4488 year: 2014 end-page: 4493 ident: bb0300 article-title: Polydopamine-functionalization of graphene oxide to enable dual signal amplification for sensitive surface Plasmon resonance imaging detection of biomarker publication-title: Anal. Chem. contributor: fullname: Li – volume: 3 start-page: 9305 year: 2015 end-page: 9314 ident: bb0275 article-title: A solution processed carbon nanotube modified conducting paper sensor for cancer detection publication-title: J. Mater. Chem. B contributor: fullname: Malhotra – volume: 8 start-page: 470 year: 2022 end-page: 483 ident: bb0050 article-title: Fabrication of poly-l-lysine-functionalized graphene quantum dots for the label-free fluorescent-based detection of carcinoembryonic antigen publication-title: ACS Biomaterials Science & Engineering contributor: fullname: Patil – volume: 4 start-page: 13469 year: 2021 end-page: 13476 ident: bb0120 article-title: Au nanoparticle-based fluorescent turn-on Nanoprobes for real-time imaging the expression of miR-630 during cell apoptosis publication-title: ACS Applied Nano Materials contributor: fullname: Huang – volume: 43 start-page: 69 year: 2013 end-page: 74 ident: bb0185 article-title: Detection of lead (II) with a “turn-on” fluorescent biosensor based on energy transfer from CdSe/ZnS quantum dots to graphene oxide publication-title: Biosens. Bioelectron. contributor: fullname: Wu – volume: 27 start-page: 1597 year: 2017 end-page: 1605 ident: bb0135 article-title: A dual-readout method for biothiols detection based on the NSET of nitrogen-doped carbon quantum dots–au nanoparticles system publication-title: J. Fluoresc. contributor: fullname: Zhang – volume: 14 year: 2021 ident: bb0015 article-title: Early lung cancer diagnostic biomarker discovery by machine learning methods publication-title: Transl. Oncol. contributor: fullname: Leung – volume: 176 start-page: 893 year: 2015 end-page: 897 ident: bb0310 article-title: Electrochemical detection of carcinoembryonic antigen based on silver nanocluster/horseradish peroxidase nanocomposite as signal probe publication-title: Electrochim. Acta contributor: fullname: Yang – volume: 7 start-page: 35982 year: 2017 end-page: 35991 ident: bb0245 article-title: Graphene oxide–metal nanocomposites for cancer biomarker detection publication-title: RSC Adv. contributor: fullname: Malhotra – volume: 6 start-page: 30849 year: 2016 ident: bb0280 article-title: Ultrasensitive sandwich-type electrochemical immunosensor based on trimetallic nanocomposite signal amplification strategy for the ultrasensitive detection of CEA publication-title: Sci. Rep. contributor: fullname: Cao – volume: 5 start-page: 10994 year: 2015 end-page: 10999 ident: bb0315 article-title: Simplified aptamer-based colorimetric method using unmodified gold nanoparticles for the detection of carcinoma embryonic antigen publication-title: RSC Adv. contributor: fullname: Wang – volume: 9 start-page: 4558 year: 2009 end-page: 4563 ident: bb0260 article-title: Long-range fluorescence quenching by gold nanoparticles in a Sandwich immunoassay for cardiac troponin T publication-title: Nano Lett. contributor: fullname: Feldmann – start-page: 1 year: 2020 end-page: 13 ident: bb0090 article-title: Nanobiosensor-based diagnostic system: Transducers and surface materials publication-title: Nanobiomaterial Engineering: Concepts and their Applications in Biomedicine and Diagnostics contributor: fullname: Dutta – volume: 2 start-page: 5513 year: 2021 end-page: 5541 ident: bb0145 article-title: Recent advances in graphene quantum dot-based optical and electrochemical (bio)analytical sensors publication-title: Materials Advances contributor: fullname: Packirisamy – volume: 4 start-page: 1 year: 2010 end-page: 10 ident: bb0020 article-title: Biosensors: the new wave in cancer diagnosis publication-title: Nanotechnol. Sci. Appl. contributor: fullname: Mousa – volume: 26 start-page: 5409 year: 1982 end-page: 5415 ident: bb0125 article-title: Electron-hole-pair quenching of excited states near a metal publication-title: Phys. Rev. B contributor: fullname: Lang – year: 2022 ident: bb0180 article-title: Recent Advances on Carbon Nanostructure-Based Biosensors, Applications of Nanomaterials in Energy Storage and Electronics Current and Future Developments in Nanomaterials and Carbon Nanotubes (Book) contributor: fullname: Packirisamy – volume: 28 start-page: 1563 year: 2019 end-page: 1579 ident: bb0045 article-title: Cancer Progress and priorities: lung Cancer publication-title: Cancer Epidemiol. Biomark. Prev. contributor: fullname: Cote – volume: 31 year: 2022 ident: bb0105 article-title: Recent advances in nanotechnology and microfluidic-based approaches for isolation and detection of circulating tumor cells (CTCs) publication-title: Nano-Structures & Nano-Objects contributor: fullname: Packirisamy – volume: 86 start-page: 3284 year: 2014 end-page: 3290 ident: bb0290 article-title: High-efficient energy funneling based on Electrochemiluminescence resonance energy transfer in graded-gap quantum dots bilayers for immunoassay publication-title: Anal. Chem. contributor: fullname: Zhu – volume: 25 start-page: 134 year: 2016 end-page: 144 ident: bb0040 article-title: The diagnostic accuracy of carcinoembryonic antigen to detect colorectal cancer recurrence - a systematic review publication-title: International Journal of Surgery (London, England) contributor: fullname: Rosenberg – volume: 23 start-page: 9 year: 2021 ident: bb0225 article-title: Optimization, fabrication, and characterization of four electrode-based sensors for blood impedance measurement publication-title: Biomed. Microdevices contributor: fullname: Manhas – volume: 704 year: 2016 ident: bb0025 article-title: Nanomaterials based biosensors for cancer biomarker detection publication-title: J. Phys. Conf. Ser. contributor: fullname: Pandey – volume: 122 start-page: 17566 year: 2018 end-page: 17574 ident: bb0130 article-title: Nano-surface energy transfer from long-lifetime terbium donors to gold nanoparticles publication-title: J. Phys. Chem. C contributor: fullname: Werts – volume: 148 year: 2020 ident: bb0240 article-title: Clinically comparable impedimetric immunosensor for serum alkaline phosphatase detection based on electrochemically engineered au-nano-Dendroids and graphene oxide nanocomposite publication-title: Biosens. Bioelectron. contributor: fullname: Chandra – volume: 3 start-page: 4922 year: 2020 end-page: 4932 ident: bb0160 article-title: Biofunctionalized graphene quantum dots based fluorescent biosensor toward efficient detection of small cell lung Cancer publication-title: ACS Applied Bio Materials contributor: fullname: Packirisamy – volume: 195 year: 2022 ident: bb0200 article-title: Ti3C2-MXene decorated with nanostructured silver as a dual-energy acceptor for the fluorometric neuron specific enolase detection publication-title: Biosens. Bioelectron. contributor: fullname: Packirisamy – volume: 763 start-page: 102 year: 2018 end-page: 110 ident: bb0230 article-title: Biofunctionalized tungsten trioxide-reduced graphene oxide nanocomposites for sensitive electrochemical immunosensing of cardiac biomarker publication-title: J. Alloys Compd. contributor: fullname: Puri – volume: 11 start-page: 19044 year: 2021 ident: bb0060 article-title: Serum carcinoembryonic antigen elevation in benign lung diseases publication-title: Sci. Rep. contributor: fullname: Yang – volume: 4 start-page: 599 year: 2011 end-page: 611 ident: bb0235 article-title: Sodium citrate: a universal reducing agent for reduction / decoration of graphene oxide with au nanoparticles publication-title: Nano Res. contributor: fullname: Tang – volume: 48 start-page: 9918 year: 2012 end-page: 9920 ident: bb0265 article-title: CEA fluorescence biosensor based on the FRET between polymer dots and au nanoparticles publication-title: Chem. Commun. contributor: fullname: Chen – volume: 102 start-page: 247 year: 2018 end-page: 255 ident: bb0220 article-title: Effect of Brownian motion on reduced agglomeration of nanostructured metal oxide towards development of efficient cancer biosensor publication-title: Biosens. Bioelectron. contributor: fullname: Malhotra – volume: 57 start-page: 303 year: 2009 end-page: 306 ident: bb0055 article-title: Serum carcinoembryonic antigen level in non-small-cell lung cancer patients with preoperative normal serum level publication-title: Gen. Thorac. Cardiovasc. Surg. contributor: fullname: Onitsuka – volume: 141 start-page: 1376 year: 2016 end-page: 1382 ident: bb0195 article-title: Self-assembled biosensor with universal reporter and dual-quenchers for detection of unlabelled nucleic acids publication-title: Analyst contributor: fullname: Hunter – volume: 6 start-page: 23406 year: 2016 ident: bb0325 article-title: Paper-based upconversion fluorescence resonance energy transfer biosensor for sensitive detection of multiple cancer biomarkers publication-title: Sci. Rep. contributor: fullname: Song – volume: 92 start-page: 342 year: 2017 end-page: 348 ident: bb0190 article-title: Target-triggered DNA nanoassembly on quantum dots and DNAzyme-modulated double quenching for ultrasensitive microRNA biosensing publication-title: Biosens. Bioelectron. contributor: fullname: Ding – volume: 284 year: 2020 ident: bb0205 article-title: Double-quencher probes improve detection sensitivity toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a reverse-transcription polymerase chain reaction (RT-PCR) assay publication-title: J. Virol. Methods contributor: fullname: Omata – volume: 30 year: 2019 ident: bb0150 article-title: Effect of sulfur doping on fluorescence and quantum yield of graphene quantum dots: an experimental and theoretical investigation publication-title: Nanotechnology contributor: fullname: Chauhan – start-page: 15 year: 2020 end-page: 47 ident: bb0095 article-title: Biosensors based on nanomaterials: Transducers and modified surfaces for diagnostics publication-title: Nanobiomaterial Engineering: Concepts and their Applications in Biomedicine and Diagnostics contributor: fullname: Picchio – start-page: 1 year: 2017 end-page: 29 ident: bb0075 article-title: Cancer biomarkers: Important tools for Cancer diagnosis and prognosis publication-title: Next Generation Point-of-Care Biomedical Sensors Technologies for Cancer Diagnosis contributor: fullname: Kunnumakkara – volume: 127 start-page: 3029 year: 2021 end-page: 3030 ident: bb0005 article-title: The ever-increasing importance of cancer as a leading cause of premature death worldwide publication-title: Cancer contributor: fullname: Soerjomataram – volume: 7 start-page: 210 year: 2023 end-page: 215 ident: bb0100 article-title: Personalized biosensors for point-of-care diagnostics: from bench to bedside applications publication-title: Nanotheranostics contributor: fullname: Chandra – volume: 3 start-page: 6989 year: 2015 end-page: 7005 ident: bb0140 article-title: Nanoparticle based fluorescence resonance energy transfer (FRET) for biosensing applications publication-title: J. Mater. Chem. B contributor: fullname: Yang – volume: 78 start-page: 497 year: 2016 end-page: 504 ident: bb0210 article-title: Nanostructured zirconia decorated reduced graphene oxide based efficient biosensing platform for non-invasive oral cancer detection publication-title: Biosens. Bioelectron. contributor: fullname: Malhotra – volume: 100 start-page: 411 year: 2018 end-page: 428 ident: bb0070 article-title: Shifting paradigm of cancer diagnoses in clinically relevant samples based on miniaturized electrochemical nanobiosensors and microfluidic devices publication-title: Biosens. Bioelectron. contributor: fullname: Chandra – volume: 52 start-page: 95 year: 2020 end-page: 101 ident: bb0035 article-title: Clinical utility of tumour marker velocity of cancer antigen 15–3 (CA 15–3) and carcinoembryonic antigen (CEA) in breast cancer surveillance publication-title: Breast contributor: fullname: Tan – volume: 9 start-page: 7431 year: 2019 end-page: 7446 ident: bb0030 article-title: Carcinoembryonic antigen carrying SLe(X) as a new biomarker of more aggressive gastric carcinomas publication-title: Theranostics contributor: fullname: Reis – volume: 71 start-page: 209 year: 2021 end-page: 249 ident: bb0010 article-title: Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries publication-title: CA Cancer J. Clin. contributor: fullname: Bray – volume: 123 year: 2020 ident: bb0170 article-title: Resonance energy transfer to gold nanoparticles: NSET defeats FRET publication-title: TrAC Trends Anal. Chem. contributor: fullname: Hildebrandt – volume: 2 year: 2021 ident: bb0165 article-title: Allium sativum derived carbon dots as a potential theranostic agent to combat the COVID-19 crisis publication-title: Sensors International contributor: fullname: Packirisamy – volume: 4 start-page: 7515 year: 2014 ident: bb0215 article-title: Synthesis of au/graphene oxide composites for selective and sensitive electrochemical detection of ascorbic acid publication-title: Sci. Rep. contributor: fullname: Song – volume: 222 year: 2023 ident: bb0155 article-title: Biomass-derived carbon nanomaterials for sensor applications publication-title: J. Pharm. Biomed. Anal. contributor: fullname: Shetti – volume: 282 start-page: 910 year: 2019 end-page: 916 ident: bb0115 article-title: A novel “OFF-ON” biosensor based on nano-surface energy transfer between gold nanocrosses and graphene quantum dots for intracellular ATP sensing and tracking publication-title: Sensors Actuators B Chem. contributor: fullname: Sun – volume: 206 start-page: 30 year: 2015 end-page: 36 ident: bb0285 article-title: An ultrasensitive electrochemical immunosensor based on the catalytical activity of MoS2-au composite using ag nanospheres as labels publication-title: Sensors Actuators B Chem. contributor: fullname: Song – volume: 73 start-page: 114 year: 2015 end-page: 122 ident: bb0305 article-title: Reduced graphene oxide modified smart conducting paper for cancer biosensor publication-title: Biosens. Bioelectron. contributor: fullname: Malhotra – volume: 86 start-page: 4188 year: 2014 end-page: 4195 ident: bb0295 article-title: Gold nanoparticle-graphite-like C3N4 Nanosheet Nanohybrids used for Electrochemiluminescent Immunosensor publication-title: Anal. Chem. contributor: fullname: Chen – volume: 9 start-page: 57 year: 2019 ident: bb0175 article-title: Gold nanoparticle surface engineering strategies and their applications in biomedicine and diagnostics publication-title: Biotech contributor: fullname: Chandra – volume: 223 year: 2023 ident: bb0085 article-title: Integrated lab-on-a-chip devices: fabrication methodologies, transduction system for sensing purposes publication-title: J. Pharm. Biomed. Anal. contributor: fullname: Chandra – volume: 137 start-page: 2593 year: 2012 end-page: 2599 ident: bb0255 article-title: Fast and sensitive dye-sensor based on fluorescein/reduced graphene oxide complex publication-title: Analyst contributor: fullname: Luo – volume: 255 start-page: 125 year: 2018 end-page: 132 ident: bb0320 article-title: Label-free electrochemical immunosensor based on flower-like ag/MoS2/rGO nanocomposites for ultrasensitive detection of carcinoembryonic antigen publication-title: Sensors Actuators B Chem. contributor: fullname: Wei – volume: 411 start-page: 985 year: 2019 end-page: 995 ident: bb0110 article-title: A novel magnetic fluorescent biosensor based on graphene quantum dots for rapid, efficient, and sensitive separation and detection of circulating tumor cells publication-title: Anal. Bioanal. Chem. contributor: fullname: Sun – volume: 141 start-page: 1376 year: 2016 ident: 10.1016/j.ijbiomac.2023.125157_bb0195 article-title: Self-assembled biosensor with universal reporter and dual-quenchers for detection of unlabelled nucleic acids publication-title: Analyst doi: 10.1039/C5AN02094H contributor: fullname: Huang – volume: 6 start-page: 23406 year: 2016 ident: 10.1016/j.ijbiomac.2023.125157_bb0325 article-title: Paper-based upconversion fluorescence resonance energy transfer biosensor for sensitive detection of multiple cancer biomarkers publication-title: Sci. Rep. doi: 10.1038/srep23406 contributor: fullname: Xu – start-page: 1 year: 2017 ident: 10.1016/j.ijbiomac.2023.125157_bb0075 article-title: Cancer biomarkers: Important tools for Cancer diagnosis and prognosis contributor: fullname: Padmavathi – volume: 4 start-page: 599 year: 2011 ident: 10.1016/j.ijbiomac.2023.125157_bb0235 article-title: Sodium citrate: a universal reducing agent for reduction / decoration of graphene oxide with au nanoparticles publication-title: Nano Res. doi: 10.1007/s12274-011-0116-y contributor: fullname: Zhang – volume: 7 start-page: 35982 year: 2017 ident: 10.1016/j.ijbiomac.2023.125157_bb0245 article-title: Graphene oxide–metal nanocomposites for cancer biomarker detection publication-title: RSC Adv. doi: 10.1039/C7RA05491B contributor: fullname: Ali – volume: 122 start-page: 17566 year: 2018 ident: 10.1016/j.ijbiomac.2023.125157_bb0130 article-title: Nano-surface energy transfer from long-lifetime terbium donors to gold nanoparticles publication-title: J. Phys. Chem. C doi: 10.1021/acs.jpcc.8b06539 contributor: fullname: Chen – volume: 704 year: 2016 ident: 10.1016/j.ijbiomac.2023.125157_bb0025 article-title: Nanomaterials based biosensors for cancer biomarker detection publication-title: J. Phys. Conf. Ser. doi: 10.1088/1742-6596/704/1/012011 contributor: fullname: Malhotra – volume: 282 start-page: 910 year: 2019 ident: 10.1016/j.ijbiomac.2023.125157_bb0115 article-title: A novel “OFF-ON” biosensor based on nano-surface energy transfer between gold nanocrosses and graphene quantum dots for intracellular ATP sensing and tracking publication-title: Sensors Actuators B Chem. doi: 10.1016/j.snb.2018.11.141 contributor: fullname: Zhang – volume: 411 start-page: 985 year: 2019 ident: 10.1016/j.ijbiomac.2023.125157_bb0110 article-title: A novel magnetic fluorescent biosensor based on graphene quantum dots for rapid, efficient, and sensitive separation and detection of circulating tumor cells publication-title: Anal. Bioanal. Chem. doi: 10.1007/s00216-018-1501-0 contributor: fullname: Cui – volume: 27 start-page: 1597 year: 2017 ident: 10.1016/j.ijbiomac.2023.125157_bb0135 article-title: A dual-readout method for biothiols detection based on the NSET of nitrogen-doped carbon quantum dots–au nanoparticles system publication-title: J. Fluoresc. doi: 10.1007/s10895-017-2095-1 contributor: fullname: Fu – volume: 9 start-page: 7431 year: 2019 ident: 10.1016/j.ijbiomac.2023.125157_bb0030 article-title: Carcinoembryonic antigen carrying SLe(X) as a new biomarker of more aggressive gastric carcinomas publication-title: Theranostics doi: 10.7150/thno.33858 contributor: fullname: Gomes – volume: 127 start-page: 3029 year: 2021 ident: 10.1016/j.ijbiomac.2023.125157_bb0005 article-title: The ever-increasing importance of cancer as a leading cause of premature death worldwide publication-title: Cancer doi: 10.1002/cncr.33587 contributor: fullname: Bray – volume: 43 start-page: 69 year: 2013 ident: 10.1016/j.ijbiomac.2023.125157_bb0185 article-title: Detection of lead (II) with a “turn-on” fluorescent biosensor based on energy transfer from CdSe/ZnS quantum dots to graphene oxide publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2012.11.039 contributor: fullname: Li – volume: 148 year: 2020 ident: 10.1016/j.ijbiomac.2023.125157_bb0240 article-title: Clinically comparable impedimetric immunosensor for serum alkaline phosphatase detection based on electrochemically engineered au-nano-Dendroids and graphene oxide nanocomposite publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2019.111815 contributor: fullname: Mahato – volume: 4 start-page: 1 year: 2010 ident: 10.1016/j.ijbiomac.2023.125157_bb0020 article-title: Biosensors: the new wave in cancer diagnosis publication-title: Nanotechnol. Sci. Appl. contributor: fullname: Bohunicky – volume: 25 start-page: 134 year: 2016 ident: 10.1016/j.ijbiomac.2023.125157_bb0040 article-title: The diagnostic accuracy of carcinoembryonic antigen to detect colorectal cancer recurrence - a systematic review publication-title: International Journal of Surgery (London, England) doi: 10.1016/j.ijsu.2015.11.065 contributor: fullname: Sørensen – volume: 48 start-page: 9918 year: 2012 ident: 10.1016/j.ijbiomac.2023.125157_bb0265 article-title: CEA fluorescence biosensor based on the FRET between polymer dots and au nanoparticles publication-title: Chem. Commun. doi: 10.1039/c2cc35645g contributor: fullname: Lin – volume: 52 start-page: 95 year: 2020 ident: 10.1016/j.ijbiomac.2023.125157_bb0035 article-title: Clinical utility of tumour marker velocity of cancer antigen 15–3 (CA 15–3) and carcinoembryonic antigen (CEA) in breast cancer surveillance publication-title: Breast doi: 10.1016/j.breast.2020.05.005 contributor: fullname: Hing – start-page: 15 year: 2020 ident: 10.1016/j.ijbiomac.2023.125157_bb0095 article-title: Biosensors based on nanomaterials: Transducers and modified surfaces for diagnostics contributor: fullname: Romero – volume: 23 start-page: 9 year: 2021 ident: 10.1016/j.ijbiomac.2023.125157_bb0225 article-title: Optimization, fabrication, and characterization of four electrode-based sensors for blood impedance measurement publication-title: Biomed. Microdevices doi: 10.1007/s10544-021-00545-4 contributor: fullname: Pradhan – volume: 4 start-page: 7515 year: 2014 ident: 10.1016/j.ijbiomac.2023.125157_bb0215 article-title: Synthesis of au/graphene oxide composites for selective and sensitive electrochemical detection of ascorbic acid publication-title: Sci. Rep. doi: 10.1038/srep07515 contributor: fullname: Song – volume: 31 year: 2022 ident: 10.1016/j.ijbiomac.2023.125157_bb0105 article-title: Recent advances in nanotechnology and microfluidic-based approaches for isolation and detection of circulating tumor cells (CTCs) publication-title: Nano-Structures & Nano-Objects doi: 10.1016/j.nanoso.2022.100886 contributor: fullname: Kumar – volume: 86 start-page: 4188 year: 2014 ident: 10.1016/j.ijbiomac.2023.125157_bb0295 article-title: Gold nanoparticle-graphite-like C3N4 Nanosheet Nanohybrids used for Electrochemiluminescent Immunosensor publication-title: Anal. Chem. doi: 10.1021/ac403635f contributor: fullname: Chen – volume: 86 start-page: 4488 year: 2014 ident: 10.1016/j.ijbiomac.2023.125157_bb0300 article-title: Polydopamine-functionalization of graphene oxide to enable dual signal amplification for sensitive surface Plasmon resonance imaging detection of biomarker publication-title: Anal. Chem. doi: 10.1021/ac5003905 contributor: fullname: Hu – volume: 206 start-page: 531 year: 2015 ident: 10.1016/j.ijbiomac.2023.125157_bb0270 article-title: An aptasensor for carcinoembryonic antigen based on upconversion fluorescence resonance energy transfer publication-title: Sensors Actuators B Chem. doi: 10.1016/j.snb.2014.09.084 contributor: fullname: Wu – volume: 102 start-page: 247 year: 2018 ident: 10.1016/j.ijbiomac.2023.125157_bb0220 article-title: Effect of Brownian motion on reduced agglomeration of nanostructured metal oxide towards development of efficient cancer biosensor publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2017.11.004 contributor: fullname: Kumar – volume: 763 start-page: 102 year: 2018 ident: 10.1016/j.ijbiomac.2023.125157_bb0230 article-title: Biofunctionalized tungsten trioxide-reduced graphene oxide nanocomposites for sensitive electrochemical immunosensing of cardiac biomarker publication-title: J. Alloys Compd. doi: 10.1016/j.jallcom.2018.04.293 contributor: fullname: Sandil – volume: 28 start-page: 1563 year: 2019 ident: 10.1016/j.ijbiomac.2023.125157_bb0045 article-title: Cancer Progress and priorities: lung Cancer publication-title: Cancer Epidemiol. Biomark. Prev. doi: 10.1158/1055-9965.EPI-19-0221 contributor: fullname: Schabath – volume: 9 start-page: 57 issue: 3 year: 2019 ident: 10.1016/j.ijbiomac.2023.125157_bb0175 article-title: Gold nanoparticle surface engineering strategies and their applications in biomedicine and diagnostics publication-title: Biotech contributor: fullname: Mahato – volume: 223 year: 2023 ident: 10.1016/j.ijbiomac.2023.125157_bb0085 article-title: Integrated lab-on-a-chip devices: fabrication methodologies, transduction system for sensing purposes publication-title: J. Pharm. Biomed. Anal. doi: 10.1016/j.jpba.2022.115120 contributor: fullname: Dkhar – volume: 7 start-page: 210 year: 2023 ident: 10.1016/j.ijbiomac.2023.125157_bb0100 article-title: Personalized biosensors for point-of-care diagnostics: from bench to bedside applications publication-title: Nanotheranostics doi: 10.7150/ntno.81485 contributor: fullname: Chandra – volume: 3 start-page: 4922 year: 2020 ident: 10.1016/j.ijbiomac.2023.125157_bb0160 article-title: Biofunctionalized graphene quantum dots based fluorescent biosensor toward efficient detection of small cell lung Cancer publication-title: ACS Applied Bio Materials doi: 10.1021/acsabm.0c00427 contributor: fullname: Kalkal – volume: 92 start-page: 342 year: 2017 ident: 10.1016/j.ijbiomac.2023.125157_bb0190 article-title: Target-triggered DNA nanoassembly on quantum dots and DNAzyme-modulated double quenching for ultrasensitive microRNA biosensing publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2016.11.002 contributor: fullname: Yuan – volume: 26 start-page: 5409 year: 1982 ident: 10.1016/j.ijbiomac.2023.125157_bb0125 article-title: Electron-hole-pair quenching of excited states near a metal publication-title: Phys. Rev. B doi: 10.1103/PhysRevB.26.5409 contributor: fullname: Persson – volume: 2 year: 2021 ident: 10.1016/j.ijbiomac.2023.125157_bb0165 article-title: Allium sativum derived carbon dots as a potential theranostic agent to combat the COVID-19 crisis publication-title: Sensors International doi: 10.1016/j.sintl.2021.100102 contributor: fullname: Kalkal – volume: 3 start-page: 9305 year: 2015 ident: 10.1016/j.ijbiomac.2023.125157_bb0275 article-title: A solution processed carbon nanotube modified conducting paper sensor for cancer detection publication-title: J. Mater. Chem. B doi: 10.1039/C5TB02169C contributor: fullname: Kumar – volume: 255 start-page: 125 year: 2018 ident: 10.1016/j.ijbiomac.2023.125157_bb0320 article-title: Label-free electrochemical immunosensor based on flower-like ag/MoS2/rGO nanocomposites for ultrasensitive detection of carcinoembryonic antigen publication-title: Sensors Actuators B Chem. doi: 10.1016/j.snb.2017.07.129 contributor: fullname: Wang – volume: 2 start-page: 5513 year: 2021 ident: 10.1016/j.ijbiomac.2023.125157_bb0145 article-title: Recent advances in graphene quantum dot-based optical and electrochemical (bio)analytical sensors publication-title: Materials Advances doi: 10.1039/D1MA00251A contributor: fullname: Kalkal – year: 2022 ident: 10.1016/j.ijbiomac.2023.125157_bb0180 contributor: fullname: Kalkal – volume: 58 start-page: 10548 year: 2022 ident: 10.1016/j.ijbiomac.2023.125157_bb0250 article-title: Stern–Volmer analysis of photocatalyst fluorescence quenching within hollow-core photonic crystal fibre microreactors publication-title: Chem. Commun. doi: 10.1039/D2CC03996F contributor: fullname: Gentleman – volume: 100 start-page: 411 year: 2018 ident: 10.1016/j.ijbiomac.2023.125157_bb0070 article-title: Shifting paradigm of cancer diagnoses in clinically relevant samples based on miniaturized electrochemical nanobiosensors and microfluidic devices publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2017.09.003 contributor: fullname: Mahato – volume: 57 start-page: 303 year: 2009 ident: 10.1016/j.ijbiomac.2023.125157_bb0055 article-title: Serum carcinoembryonic antigen level in non-small-cell lung cancer patients with preoperative normal serum level publication-title: Gen. Thorac. Cardiovasc. Surg. doi: 10.1007/s11748-008-0397-6 contributor: fullname: Tomita – start-page: 1 year: 2020 ident: 10.1016/j.ijbiomac.2023.125157_bb0090 article-title: Nanobiosensor-based diagnostic system: Transducers and surface materials contributor: fullname: Dutta – volume: 86 start-page: 3284 year: 2014 ident: 10.1016/j.ijbiomac.2023.125157_bb0290 article-title: High-efficient energy funneling based on Electrochemiluminescence resonance energy transfer in graded-gap quantum dots bilayers for immunoassay publication-title: Anal. Chem. doi: 10.1021/ac500351d contributor: fullname: Ji – volume: 30 year: 2019 ident: 10.1016/j.ijbiomac.2023.125157_bb0150 article-title: Effect of sulfur doping on fluorescence and quantum yield of graphene quantum dots: an experimental and theoretical investigation publication-title: Nanotechnology doi: 10.1088/1361-6528/ab3566 contributor: fullname: Kadian – volume: 123 year: 2020 ident: 10.1016/j.ijbiomac.2023.125157_bb0170 article-title: Resonance energy transfer to gold nanoparticles: NSET defeats FRET publication-title: TrAC Trends Anal. Chem. doi: 10.1016/j.trac.2019.115748 contributor: fullname: Chen – volume: 284 year: 2020 ident: 10.1016/j.ijbiomac.2023.125157_bb0205 article-title: Double-quencher probes improve detection sensitivity toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a reverse-transcription polymerase chain reaction (RT-PCR) assay publication-title: J. Virol. Methods doi: 10.1016/j.jviromet.2020.113926 contributor: fullname: Hirotsu – volume: 3 start-page: 6989 year: 2015 ident: 10.1016/j.ijbiomac.2023.125157_bb0140 article-title: Nanoparticle based fluorescence resonance energy transfer (FRET) for biosensing applications publication-title: J. Mater. Chem. B doi: 10.1039/C5TB00885A contributor: fullname: Shi – volume: 4 start-page: 13469 year: 2021 ident: 10.1016/j.ijbiomac.2023.125157_bb0120 article-title: Au nanoparticle-based fluorescent turn-on Nanoprobes for real-time imaging the expression of miR-630 during cell apoptosis publication-title: ACS Applied Nano Materials doi: 10.1021/acsanm.1c02967 contributor: fullname: Lin – volume: 195 year: 2022 ident: 10.1016/j.ijbiomac.2023.125157_bb0200 article-title: Ti3C2-MXene decorated with nanostructured silver as a dual-energy acceptor for the fluorometric neuron specific enolase detection publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2021.113620 contributor: fullname: Kalkal – volume: 78 start-page: 497 year: 2016 ident: 10.1016/j.ijbiomac.2023.125157_bb0210 article-title: Nanostructured zirconia decorated reduced graphene oxide based efficient biosensing platform for non-invasive oral cancer detection publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2015.11.084 contributor: fullname: Kumar – volume: 222 year: 2023 ident: 10.1016/j.ijbiomac.2023.125157_bb0155 article-title: Biomass-derived carbon nanomaterials for sensor applications publication-title: J. Pharm. Biomed. Anal. doi: 10.1016/j.jpba.2022.115102 contributor: fullname: Malode – volume: 6 start-page: 30849 year: 2016 ident: 10.1016/j.ijbiomac.2023.125157_bb0280 article-title: Ultrasensitive sandwich-type electrochemical immunosensor based on trimetallic nanocomposite signal amplification strategy for the ultrasensitive detection of CEA publication-title: Sci. Rep. doi: 10.1038/srep30849 contributor: fullname: Tian – volume: 11 start-page: 19044 year: 2021 ident: 10.1016/j.ijbiomac.2023.125157_bb0060 article-title: Serum carcinoembryonic antigen elevation in benign lung diseases publication-title: Sci. Rep. doi: 10.1038/s41598-021-98513-8 contributor: fullname: Yang – volume: 14 year: 2021 ident: 10.1016/j.ijbiomac.2023.125157_bb0015 article-title: Early lung cancer diagnostic biomarker discovery by machine learning methods publication-title: Transl. Oncol. doi: 10.1016/j.tranon.2020.100907 contributor: fullname: Xie – volume: 8 start-page: 470 year: 2022 ident: 10.1016/j.ijbiomac.2023.125157_bb0050 article-title: Fabrication of poly-l-lysine-functionalized graphene quantum dots for the label-free fluorescent-based detection of carcinoembryonic antigen publication-title: ACS Biomaterials Science & Engineering doi: 10.1021/acsbiomaterials.1c01087 contributor: fullname: Tade – start-page: 115 year: 2017 ident: 10.1016/j.ijbiomac.2023.125157_bb0080 article-title: Point-of-care and implantable biosensors in Cancer research and diagnosis contributor: fullname: Siontorou – volume: 73 start-page: 114 year: 2015 ident: 10.1016/j.ijbiomac.2023.125157_bb0305 article-title: Reduced graphene oxide modified smart conducting paper for cancer biosensor publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2015.05.040 contributor: fullname: Kumar – ident: 10.1016/j.ijbiomac.2023.125157_bb0065 doi: 10.1016/B978-0-12-818154-6.00008-1 – ident: 10.1016/j.ijbiomac.2023.125157_bb5000 doi: 10.1109/TIM.2023.3275998 – volume: 9 start-page: 4558 year: 2009 ident: 10.1016/j.ijbiomac.2023.125157_bb0260 article-title: Long-range fluorescence quenching by gold nanoparticles in a Sandwich immunoassay for cardiac troponin T publication-title: Nano Lett. doi: 10.1021/nl903178n contributor: fullname: Mayilo – volume: 5 start-page: 10994 year: 2015 ident: 10.1016/j.ijbiomac.2023.125157_bb0315 article-title: Simplified aptamer-based colorimetric method using unmodified gold nanoparticles for the detection of carcinoma embryonic antigen publication-title: RSC Adv. doi: 10.1039/C4RA14833A contributor: fullname: Luo – volume: 71 start-page: 209 year: 2021 ident: 10.1016/j.ijbiomac.2023.125157_bb0010 article-title: Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries publication-title: CA Cancer J. Clin. doi: 10.3322/caac.21660 contributor: fullname: Sung – volume: 137 start-page: 2593 year: 2012 ident: 10.1016/j.ijbiomac.2023.125157_bb0255 article-title: Fast and sensitive dye-sensor based on fluorescein/reduced graphene oxide complex publication-title: Analyst doi: 10.1039/c2an35099h contributor: fullname: Huang – volume: 176 start-page: 893 year: 2015 ident: 10.1016/j.ijbiomac.2023.125157_bb0310 article-title: Electrochemical detection of carcinoembryonic antigen based on silver nanocluster/horseradish peroxidase nanocomposite as signal probe publication-title: Electrochim. Acta doi: 10.1016/j.electacta.2015.07.086 contributor: fullname: Quan – volume: 206 start-page: 30 year: 2015 ident: 10.1016/j.ijbiomac.2023.125157_bb0285 article-title: An ultrasensitive electrochemical immunosensor based on the catalytical activity of MoS2-au composite using ag nanospheres as labels publication-title: Sensors Actuators B Chem. doi: 10.1016/j.snb.2014.09.028 contributor: fullname: Wang |
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