On‐Demand Continuous Flow Synthesis of Pentafluorosulfanyl Chloride (SF5Cl) Using a Custom‐Made Stirring Packed‐Bed Reactor

• Published in: Chemistry : a European journal Vol. 31; no. 14; pp. e202404039 - n/a
• Main Authors: Peyrical, Lauriane C., Mabit, Thibaud, Kairouz, Vanessa, Charette, André B.
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 06.03.2025
• Subjects: Alkynes; Chlorides; Continuous flow; continuous flow chemistry; custom-made stirring packed-bed reactor; pentafluorosulfanyl; Potassium fluoride; radical reactions; Reactors; Reagents; Stirring; Sulfur; Synthesis; radical reactions; custom-made stirring packed-bed reactor; continuous flow chemistry; pentafluorosulfanyl

The pentafluorosulfanyl (SF5−) group has been the subject of a surge of interest in the past decade, but there is still little practicality associated with its synthesis and installation. Herein is reported the first continuous flow synthesis of pentafluorosulfanyl chloride (SF5Cl), the most common...