Geranylation of Cyclic Dipeptides and Naphthols by the Fungal Prenyltransferase CdpC3PT_F253G

• Published in: Chembiochem : a European journal of chemical biology Vol. 26; no. 3; pp. e202400787 - n/a
• Main Authors: Li, Dan, Wang, Yi, Xu, Yuanyuan, Long, Hongping, Min, Wenqing, Gao, Shangfeng, Li, Shu‐Ming, Yu, Xia
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 01.02.2025; Wiley Subscription Services, Inc
• Subjects: Antiinfectives and antibacterials; Bacillus subtilis; Biocatalysis; Biocatalysts; Biochemistry & Molecular Biology; Biological activity; Biosynthesis; Chemical synthesis; Chemistry, Medicinal; Cyclic dipeptides; Dimethylallyltranstransferase - chemistry; Dimethylallyltranstransferase - genetics; Dimethylallyltranstransferase - metabolism; Dipeptides - chemistry; Dipeptides - metabolism; Geranylation; Life Sciences & Biomedicine; Naphthols; Naphthols - chemistry; Naphthols - metabolism; Neosartorya - enzymology; Peptides, Cyclic - chemistry; Peptides, Cyclic - metabolism; Pharmacology & Pharmacy; Prenylation; Prenyltransferases; Science & Technology; Transferase; Tryptophan; Biocatalysis; Transferase; PIPERAZINE-2,5-DIONE; Naphthols; PRENYLATION; ENZYMES; Cyclic dipeptides; Geranylation; HYDROXYNAPHTHALENES

Prenyl modification often improves the biological activities of compounds. Prenyltransferases have attracted attention as environmentally friendly biocatalysts for catalyzing prenyl modification of compounds. Compared to dimethylallyl modifications, research on geranyl modifications is relatively li...