Production of Biobased Ethylbenzene by Cascade Biocatalysis with an Engineered Photodecarboxylase

• Published in: Angewandte Chemie International Edition Vol. 63; no. 8; pp. e202314566 - n/a
• Main Authors: Qin, Zhaoyang, Zhou, Yi, Li, Zhi, Höhne, Matthias, Bornscheuer, Uwe T., Wu, Shuke
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 19.02.2024
• Edition: International ed. in English
• Subjects: Benzene; Benzene - metabolism; Benzene Derivatives - metabolism; Biocatalysis; Cascade chemical reactions; Catalysis; Commodities; Enzyme Cascades; Ethyl benzene; Ethylbenzene; Fermentation; Phenylalanine; Phenylalanine - metabolism; Photodecarboxylase; Protein Engineering; Renewable Resources; Sustainable yield; Toluene; Toluene - metabolism; Xylenes; Renewable Resources; Biocatalysis; Enzyme Cascades; Protein Engineering; Photodecarboxylase

Production of commodity chemicals, such as benzene, toluene, ethylbenzene, and xylenes (BTEX), from renewable resources is key for a sustainable society. Biocatalysis enables one‐pot multistep transformation of bioresources under mild conditions, yet it is often limited to biochemicals. Herein, we d...